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Gliclazide
go.drugbank.com/drugs/DB01120ApprovedInvestigationalMedications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. … The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals.
Categories: Drugs Used in DiabetesProducts: Gliavis IR Tablet 80mgArnica montana
go.drugbank.com/drugs/DB14297InvestigationalArnica montana is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: European Arnica WholePhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
go.drugbank.com/bio_entities/BE0005530TargetHumansInvolved in the regulation of synaptic function in excitatory hippocampal synapses. … May be a negative regulator of insulin signaling and glucose metabolism in adipose tissue.
Synonyms: Mutated in multiple advanced cancers 1tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
go.drugbank.com/bio_entities/BE0020091EnzymeHumansSpecifically modifies U20 in cytoplasmic tRNAs (PubMed:38680565). Activity depends on the presence of guanosine at position 19 in the tRNA substrate (PubMed:38680565). … Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:15994936, PubMed:26429968, PubMed:30149704, PubMed:34798057, PubMed:38680565).
Synonyms: Up-regulated in lung cancer protein 8Splinter
go.drugbank.com/conditions/DBCOND0015551Drugs: IchthammolSynonyms: Splinter in skin (disorder)Amoxicillin
go.drugbank.com/drugs/DB01060ApprovedInvestigationalVet approvedAmoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. … [A190648] Amoxicillin was granted FDA approval on 18 January 1974.[L11644]
Mixtures: CROXILEX 1.2G IV ENJEKSİYON İÇİN TOZ İÇEREN FLAKON, Amoklavin 1000 mg/200 mg IV Enjeksiyonluk/İnfüzyonluk Çözelti Hazırlamak İçin Toz ve ÇözücüProducts: NEOAMOX 500MG IM/IV ENJEKSİYONLUK TOZ, 1 ADET, NEOAMOX 1 GR IM/IV ENJEKSİYONLUK TOZ, 1 ADETLansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigational[A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) … Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole.
Products: Prevacid IVTranscription factor p65
go.drugbank.com/bio_entities/BE0005551TargetHumansNF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … Essential for cytokine gene expression in T-cells (PubMed:15790681). The NF-kappa-B homodimeric RELA-RELA complex appears to be involved in invasin-mediated activation of IL-8 expression.
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3Serine/threonine-protein kinase Nek1
go.drugbank.com/bio_entities/BE0009496TargetHumansInvolved in cilium assembly (PubMed:21211617) … In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (PubMed:20230784). May be implicated in the control of meiosis (By similarity).
Synonyms: Never in mitosis A-related kinase 1Nuclear factor NF-kappa-B
go.drugbank.com/bio_entities/BE0004903TargetHumansNF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family.
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1