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Displaying results 1031 - 1040 of 10000 in total
  1. Drug

    Lobaplatin

    go.drugbank.com/drugs/DB13049
    Investigational

    Lobaplatin has been used in trials studying the treatment of Breast Cancer, Hepatocellular Carcinoma, and Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma.

  2. Drug

    AVB-001

    go.drugbank.com/drugs/DB18452
    Investigational

    AVB-001 is an encapsulated, engineered human ARPE-19 cell line that constitutively expresses the native human IL-2 cytokine

  3. Drug

    Oxaliplatin

    go.drugbank.com/drugs/DB00526
    ApprovedInvestigational

    [A796,A797] This is an effective combination treatment both as a first-line treatment and in patients refractory to an initial fluorouracil and leucovorin combination. … Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin.

    Synonyms: L-OHP, (SP-4-2-(1R-TRANS))-(1,2-CYCLOHEXANEDIAMINE-N,N')(ETHANEDIOATO(2-)-O,O')PLATINUMCategories: OCT2 Substrates with a Narrow Therapeutic Index
  4. Drug

    Enzacamene

    go.drugbank.com/drugs/DB11219
    Approved

    Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. … While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and cosmetic products is approved by Health Canada.

    Synonyms: Enzacamene D-L formMixtures: Outback 2-in-1 Insect Repellent and Protective Sunscreen, Anthelios L-lait Ecran Intol.solaire SPF 60
  5. Drug

    Angiotensin II

    go.drugbank.com/drugs/DB11842
    ApprovedInvestigational

    As distributive shock is the most common type of shock in the inpatient setting and affects up to one third of patients in the intensive care unit, the FDA determined that there is a need for treatment … As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's Giapreza (angiotensin II) Injection for Intravenouse Infusion for the indication of acting as a vasoconstrictor to increase blood pressure

    Synonyms: 5-L-isoleucineangiotensin II
  6. Drug

    AVR118

    go.drugbank.com/drugs/DB04979
    Investigational

    AVR118 represents a new type of biopolymer chemistry that also possesses novel immunomodulator activity. … AVR118 is being studied for the promise shown in its ability to mitigate the toxic side effects of other drugs (including those used to treat HIV infection and chemotherapeutic drugs employed in the treatment

  7. Drug

    SQ-109

    go.drugbank.com/drugs/DB05186
    Investigational

    Currently in Phase I clinical trials, SQ-109 could replace one or more drugs in the current first-line TB drug regimen, simplify therapy, and shorten the TB treatment regimen. … SQ-109 is an orally active, small molecule antibiotic for treatment of pulmonary TB.

    Synonyms: N-adamantanyl-N'-geranyl-ethylenediamine
  8. Drug

    Famtozinameran

    go.drugbank.com/drugs/DB17088
    ApprovedInvestigational

    The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. … [L43917] Famtozinameran is an mRNA vaccine encoding the S glycoprotein of SARS-CoV-2 Omicron variant lineages BA.4 and BA.5.

    Mixtures: Comirnaty Original & Omicron Ba.4/ba.5, Comirnaty Original & Omicron Ba.4/ba.5
  9. Drug

    Carbon monoxide

    go.drugbank.com/drugs/DB11588
    ApprovedInvestigational

    The European Union has banned the use of carbon monoxide as a color stabilizer in meat and fish. … Exhaled CO (eCO), similar to exhaled nitric oxide (eNO), has been evaluated as a candidate breath biomarker of pathophysiological states, including smoking status, and inflammatory diseases of the lung

    Mixtures: Co-NE-O2-N2 Mixture, Lung Diffusion Test Mix No Ne Co
  10. Drug

    Heparin

    go.drugbank.com/drugs/DB01109
    ApprovedInvestigational

    partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. … UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated

    Mixtures: Heparin Sodium in Dextrose, Heparin Sodium in DextroseProducts: Heparin Sodium in Dextrose, Heparin Sodium in Sodium Chloride