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Fibrinogen human
go.drugbank.com/drugs/DB09222ApprovedInvestigationalIt is a soluble plasma glycoprotein with a molecular weight of about 340 kDa and is a physiological substrate for three enzymes: plasmin, factor XIIIa, and thrombin. … Fibrinogen concentrate (human) is a hematological agent. It works by replacing a specific protein in the blood, fibrinogen (factor I), that helps with blood clotting.
Mixtures: EVICEL® SELLANTE DE FIBRINA HUMANA, TISSEEL FIBRIN SEALANT VH S/D (FROZEN)Lipegfilgrastim
go.drugbank.com/drugs/DB13200ApprovedThe average molecular mass of lipegfilgrastim comprises 18,798 Da for [DB00099], 203 Da for GalNAc, 338 Da for glycylsialic acid and approximately 20,000 Da for PEG [L2449]. … Lipegfilgrastim is a covalent conjugate of [DB00099] with a single methoxy polyethylene glycol (PEG) molecule via a carbohydrate linker consisting of glycine, N-acetylneuraminic acid and N-acetylgalactosamine
Capmatinib
go.drugbank.com/drugs/DB11791ApprovedInvestigationalday. … Capmatinib is a small molecule kinase inhibitor targeted against c-Met (a.k.a. hepatocyte growth factor receptor [HGFR]), a receptor tyrosine kinase that, in healthy humans, activates signaling cascades
Memantine
go.drugbank.com/drugs/DB01043ApprovedInvestigationalInitially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). … In December 2013, the G8 dementia summit concluded that dementia should be considered a global priority with the objective of developing a cure or a disease-modifying therapy by the year 2025 [L5953, F4366
Categories: N-methyl-D-aspartate Receptor AntagonistProducts: MEMANTIN 1A PHARMA 10MG, MEMANTIN 1A PHARMA 20MGEravacycline
go.drugbank.com/drugs/DB12329ApprovedInvestigationalIt was first approved by the FDA on August 27, 2018 [L4540]. … Eravacycline, known as _Xerava_ by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive
Categories: Monoamine Oxidase A SubstratesAcyclovir
go.drugbank.com/drugs/DB00787ApprovedInvestigational[L7321] Acyclovir was granted FDA approval on 29 March 1982.[L7318] … Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and acute herpetic keratitis.
Categories: Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor, Herpes Zoster Virus Nucleoside Analog DNA Polymerase InhibitorProducts: Aciclovir 1A Pharma - Creme, ACICLOVIR 200 1A PHARMAHistidine
go.drugbank.com/drugs/DB00117ApprovedInvestigationalNutraceuticalAn essential amino acid that is required for the production of histamine.
Synonyms: (S)-a-Amino-1H-imidazole-4-propanoic acidMixtures: SOLUCION DP-AMINE, TRAVASOL PLUS 15% LIBRE DE BISULFITOBuspirone
go.drugbank.com/drugs/DB00490ApprovedInvestigationalBuspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. … Belonging to the azaspirodecanedione drug class,[A180991] buspirone is a serotonin 5-HT<sub>1A</sub> receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates
Categories: Dopamine D2 Receptor AntagonistsEnzacamene
go.drugbank.com/drugs/DB11219ApprovedCommonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter.
Mixtures: Rejuva Moisturizing Day Cream SPF 30, Bain De Soleil Protection Lotion SPF 15Synonyms: Enzacamene D-L form, 3-(p-Methylbenzylidene)-DL-camphorMitochondrial ATP synthase F1 domain
go.drugbank.com/bio_entities/BE0010209TargetEnzymeHumansPart of the complex F(0) domain (PubMed:37244256). … ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256).
Polypeptides: ATP synthase F(1) complex subunit alpha, mitochondrial, ATP synthase F(1) complex subunit beta, mitochondrial