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Acetrizoic acid
go.drugbank.com/drugs/DB09347ApprovedWithdrawn[L1704] Acetrizoic acid presents, in the FDA records, a category of drug substance with an inactive status.[L1703] … Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid[L1702] and it is the first monomeric ionic compound used as an X-ray contrast agent.
Categories: Compounds used in a research, industrial, or household settingGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. … [A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers.
Neomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approved[L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. … [A175042,A191529] Neomycin A, or [neamine], is a moiety that conjoins two molecules of neomycin B and C together.
Mixtures: AK-Trol, WELL AT WALG TRIPLE ANTIBIOTIC Well at WalgreensCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexGilteritinib
go.drugbank.com/drugs/DB12141ApprovedInvestigationalThis drug was approved after being designed as an orphan drug with a fast track and priority review status.[L4830] … Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group.
Fluoroestradiol F-18
go.drugbank.com/drugs/DB15690ApprovedInvestigationalFluoroestradiol F-18 is an imaging agent used with positron emission tomography (PET) to detect estrogen receptor-positive breast cancer lesions.
Iopromide
go.drugbank.com/drugs/DB09156ApprovedIt functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs … Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration.
Categories: Compounds used in a research, industrial, or household settingNimodipine
go.drugbank.com/drugs/DB00393ApprovedInvestigationalNimodipine is used to as an adjunct to improve the neurologic outcome following subarachnoid hemorrhage from ruptured intracranial aneurysm. … Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.
Synonyms: isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylateProducts: NIMODIPINA DOC GENERICI, NIMODIPINA MYLAN GENERICSFludrocortisone
go.drugbank.com/drugs/DB00687ApprovedInvestigational[A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position … Fludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace missing endogenous corticosteroids in patients with adrenal insufficiency.
Quinupramine
go.drugbank.com/drugs/DB13246ApprovedQuinupramine has been approved in France under the brand name Kinupril, as an antidepressant [A175003].
Lomitapide
go.drugbank.com/drugs/DB08827Approved[A7367] Lomitapide was first approved by the FDA in December 2012 and the EMA in July 2013 as an adjunct to a low-fat diet and other lipid-lowering treatments.[A275444, A275446] … [A275445, A7367] This makes it a critical therapeutic option for "receptor-negative" patients who have little to no functional LDL receptor activity.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index