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Displaying results 1051 - 1060 of 8573 in total
  1. Drug

    Somatrem

    go.drugbank.com/drugs/DB09098
    ApprovedWithdrawn

    Despite the ability of almost all contemporary recombinant growth hormones to cause definite and demonstrable increases in growth rate in patients who are administered the drug, the use of these agents continues to be mired in persistent...

    Mixtures: Protropin Inj Pws 10mg/vial, Protropin - Kit Im Sc 10mg/vial
  2. Drug

    Cholecystokinin

    go.drugbank.com/drugs/DB08862
    ApprovedInvestigationalWithdrawn

    CCK also acts as an appetite suppressant and has been studied for weight management regimens [L1637]. … Soon after, it was recognized to be identical to the factor responsible for stimulating pancreatic exocrine secretion in 1943 [L1636].

  3. Drug

    Edaravone

    go.drugbank.com/drugs/DB12243
    ApprovedInvestigational

    [A254257] It has three tautomers. … [L44017] Edaravone was initially granted orphan designation by the European Medicines Agency on June 19, 2015 [L44007] and was under regulatory review in Europe.

  4. Drug

    Propoxycaine

    go.drugbank.com/drugs/DB09342
    Approved

    This drug was removed from the US market in 1996. … Used in combination with procaine, it was the only dental local anesthetic available in cartridge form [L1592].

  5. Drug

    Trifluridine

    go.drugbank.com/drugs/DB00432
    ApprovedInvestigational

    The combination product of trifluridine with tipiracil marketed as Lonsurf has been approved in Japan, the United States, and the European Union for the treatment of adult patients with metastatic colorectal … cancer who have been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and if RAS wild-type, an anti-EGFR therapy.

  6. Drug

    Silicon dioxide

    go.drugbank.com/drugs/DB11132
    Approved

    It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite as transparent and tasteless crystals. … In powdered food products and pharmaceutical tablets, silicon dioxide is added as a flow agent to absorb water. Colloidal silica is also used as a wine, beer, and juice fining agent or stabilizer.

    Mixtures: E-Z-gas II, PediaCare Infants Gas Relief
  7. Drug

    Florbetapir F-18

    go.drugbank.com/drugs/DB09149
    ApprovedInvestigational

    The radionucleide fluorine-18 was chosen as it has a half life of 110 minutes allowing it to accumulate sufficiently in the brain before undergoing positon emission decay. … Marketed as the product Amyvid, florbetapir 18F is indicated for positron emission tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment

  8. Drug

    Segesterone acetate

    go.drugbank.com/drugs/DB14583
    Approved

    As with other hormonal contraceptives, Annovera™ carries the risk for serious cardiovascular events. … Annovera™ is administered as a vaginal ring that is in place for 21 days and removed for 7 days each cycle.

  9. Drug

    Relatlimab

    go.drugbank.com/drugs/DB14851
    ApprovedInvestigational

    [L41265,L41300] It was the first anti-LAG-3 antibody to demonstrate benefit in a Phase 3 study, as well as the first to receive FDA approval. … [A246165,L41265] It was the first commercially developed anti-LAG-3 antibody, entering clinical trials in 2013,[A246155] and has garnered interest in the treatment of a variety of cancers, including leukemia

  10. Drug

    Iophendylate

    go.drugbank.com/drugs/DB01187
    Approved

    Iophendylate, which was never shown to be safe, was initially introduced for use in small amounts (1-2cc) for locating spinal tumors. … Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231).