Search

Displaying results 1051 - 1060 of 10000 in total

Drug
Dequalinium
go.drugbank.com/drugs/DB04209
Approved
Due to its flexible structure, dequalinium was investigated to build drug and gene delivery systems. … [A249255] It is a quaternary ammonium compound,[L42190] as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain.
Products: Fluomizin 10 mg Vaginaltabletten, DONAXYL 10 MG VAJİNAL TABLET, 6 ADET
Drug
Desipramine
go.drugbank.com/drugs/DB01151
Approved
The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … See toxicity section below for a complete listing of side effects.
Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesProducts: DESIPRAM 25 MG TABLET, 100 ADET, Desipramine-10 - Tab 10mg
Drug
Raltegravir
go.drugbank.com/drugs/DB06817
ApprovedInvestigational
Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. … Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Products: Chewable Tablet 100 mg, ISENTRESS® GRÁNULOS PARA SUSPENSIÓN ORAL 100 MG
Drug
Lomitapide
go.drugbank.com/drugs/DB08827
Approved
Lomitapide, marketed under the brand names Juxtapid (USA) and Lojuxta (EU), is a first-in-class, small-molecule inhibitor of microsomal triglyceride transfer protein (MTP). … [A7367] Lomitapide was first approved by the FDA in December 2012 and the EMA in July 2013 as an adjunct to a low-fat diet and other lipid-lowering treatments.[A275444, A275446]
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A InhibitorsProducts: JUXTAPID CAPSULAS POR 10 MG, JUXTAPID® CÁPSULAS POR 20 MG
Drug
Pimozide
go.drugbank.com/drugs/DB01100
Approved
A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome.
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: NOROFREN 2 MG TABLET, 10 ADET, NOROFREN 2 MG TABLET, 20 ADET
Drug
Rofecoxib
go.drugbank.com/drugs/DB00533
ApprovedWithdrawn
Rofecoxib has a half-life of 17 hours and its mean oral bioavailability at therapeutically recommended doses of 125, 25, and 50 mg is approximately 93%. … The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: COXDOS 50 MG, ROFECOXIB 50 MG
Drug
Manganese gluconate
go.drugbank.com/drugs/DB11141
Approved
Manganese gluconate is a direct ingredient in food substances as a nutrient supplement. In pharmaceutical preparations it is used as a [DB06757] supplement. … Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O.
Synonyms: Manganese D-gluconateMixtures: Vitamin E 400 Iu With Selenium, Vitamin C & Manganese, Vital Be-100
Drug
Propylthiouracil
go.drugbank.com/drugs/DB00550
Approved
A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine.
Products: PROPYL TABLET 50 mg, LOXAN 250 MG..(TABLETAS)
Drug
Influenza A virus A/Darwin/9/2021 SAN-010 (H3N2) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB16916
Approved
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde.
Synonyms: Influenza A virus A/Darwin/9/2021 SAN-010 (H3N2) antigen (formaldehyde inactivated)Categories: Inactivated Influenza A Virus Vaccine
Drug
Cefazolin
go.drugbank.com/drugs/DB01327
ApprovedInvestigational
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Mixtures: CEFAMEZIN 250 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET, CEFAMEZIN 500 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADETProducts: CEFAZOLINA SÓDICA 1 G / VIAL POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE, SEFAZOL 250 MG IM/IV ENJEKSİYONLUK TOZ İÇEREN FLAKON, 10 ADET