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PF-03654746
go.drugbank.com/drugs/DB12201InvestigationalPF-03654746 has been investigated for the treatment of Narcolepsy, Schizophrenia, Tourette's Syndrome, and Excessive Daytime Sleepiness.
Ebvaciclib
go.drugbank.com/drugs/DB18967InvestigationalEbvaciclib is under investigation in clinical trial NCT03519178 (A Study of PF-06873600 in People With Cancer).
Mosliciguat
go.drugbank.com/drugs/DB19425InvestigationalMosliciguat is under investigation in clinical trial NCT06635850 (A Phase 2 Study of Mosliciguat in PH-ILD).
NOV-002
go.drugbank.com/drugs/DB05393InvestigationalIt has been administered to over 10,000 patients, demonstrating clinical efficacy and excellent safety data.
Zinc gluconate
go.drugbank.com/drugs/DB11248ApprovedInvestigationalVet approvedIt is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.
Mycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigationalA180799,A180805] Previously, mycophenolic acid (MPA) was administered to individuals with autoimmune diseases beginning in the 1970s, but was discontinued due to gastrointestinal effects and concerns over
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesTetryzoline
go.drugbank.com/drugs/DB06764ApprovedTetryzoline is found in a wide array of over-the-counter eye drops, including the most common brand, Visine.
Plazomicin
go.drugbank.com/drugs/DB12615ApprovedHowever, acquired resistance of aminoglycosides may arise through over expression of efflux pumps and ribosomal modification by bacteria, which results from amino acid or rRNA sequence mutations [A33942
Vedolizumab
go.drugbank.com/drugs/DB09033ApprovedInvestigational[A261576] Vedolizumab is administered by IV infusion over a period of 30 minutes; after the first dose, it is given again at two and six weeks and then every 8 weeks thereafter.
Silodosin
go.drugbank.com/drugs/DB06207ApprovedInvestigational[L32368] Most commonly affecting males over the age of 40 years, benign prostatic hyperplasia is the non-malignant enlargement of the prostate gland, associated with lower urinary tract symptoms that have
Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates