Search
Relatlimab
go.drugbank.com/drugs/DB14851ApprovedInvestigational[L41305] As immune checkpoint inhibitors have limited efficacy when used alone, drugs like relatlimab have been trialed in combination with other checkpoint inhibitors - for example, PD-1 inhibitors like … [A246155] Relatlimab received FDA approval in March 2022, alongside the PD-1 inhibitor [nivolumab] in the combination product Opdualag (Bristol-Myers Squibb), for the treatment of unresectable or metastatic
Oxyquinoline
go.drugbank.com/drugs/DB11145ApprovedInvestigationalVet approvedIt is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Mixtures: Fem pH, Trimo SanCategories: Antiinfectives and Antiseptics for Local Oral TreatmentAspartic acid
go.drugbank.com/drugs/DB00128ApprovedInvestigationalNutraceuticalIt may be a neurotransmitter.
Mixtures: Aminosyn-PF, Aminosyn-PFChromium
go.drugbank.com/drugs/DB11136ApprovedInvestigationalChromium chloride is available as an intravenous injection for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN) [FDA Label]. … Chromium picolinate capsules may be used as nutritional adjuvant in patients with or at risk of type 2 diabetes mellitus (T2DM) to improve blood sugar metabolism and stabilize the levels of serum cholesterol
Mixtures: Doctor's Choice Brand for Men, Multivitamins and Minerals for MenEnapotamab vedotin
go.drugbank.com/drugs/DB16156InvestigationalEnapotamab vedotin is under investigation in clinical trial NCT02988817 (Enapotamab Vedotin (Humax-axl-adc) Safety Study in Patients With Solid Tumors).
Synonyms: Immunoglobulin g1, anti-(human growth factor receptor axl)(human humax-axl .gamma.1-chain), disulfide with human humax-axl .kappa.-chain, dimer tetrakis(thioether) with vedotinMargetuximab
go.drugbank.com/drugs/DB14967ApprovedInvestigationalThe HER2 oncoprotein, the product of the human _ERBB2_/mouse _neu_ genes, is a member of the HER family of receptor tyrosine kinases that includes the epidermal growth factor receptor (EGFR). … [A225756] Margetuximab (formerly MGAH22) is an Fc-engineered human/mouse chimeric anti-HER2 IgG1κ monoclonal antibody derived from the same mouse 4D5 clone that [trastuzumab] is derived from and is
Categories: HER2 Receptor Antagonists, HER2 (Human Epidermal Growth Factor Receptor 2) inhibitorsOctocrylene
go.drugbank.com/drugs/DB09535ApprovedOctocrylene may cause contact and photocontact allergy. … However, the use of this chemical doesn’t just stop with sunscreen for face and arms, but can extend to a variety of other products, like hair spray, tannin oil, BB cream, conditioner, and CC cream, among
Mixtures: Tree Hut Dry Oil Mist Daily Defense SPF8, Tree Hut DD Cream Daily Defense Cream SPF20Testosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationalThe majority of the prescriptions written were for injectable (66%) and topical (32%) testosterone products. As recent as 1 October 2018, the US FDA approved Antares Pharma Inc.' … reduces the need for in-office/in-clinic injection procedures that may inconvenience patients with frequent visits to the clinic [L4659].
Categories: Hormonal Contraceptives for Systemic Use, P-glycoprotein inhibitorsSugemalimab
go.drugbank.com/drugs/DB16641ApprovedInvestigational[L53333] In combination with platinum-based chemotherapy, sugemalimab is a first-line treatment indicated for adult populations with metastatic non-small cell lung cancer (NSCLC) with no sensitising EGFR … Sugemalimab is a fully human, full-length anti-programmed death-ligand 1 (PD-L1) monoclonal antibody (of the IgG4 isotype) discovered by CStone Pharmaceuticals.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsMAP kinase-interacting serine/threonine-protein kinase 1
go.drugbank.com/bio_entities/BE0009488TargetHumansMay play a role in the response to environmental stress and cytokines.
Polypeptides: MAP kinase-interacting serine/threonine-protein kinase 1Synonyms: MAP kinase signal-integrating kinase 1