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Diphenidol
go.drugbank.com/drugs/DB01231ApprovedWithdrawnDiphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. Diphenidol overdose may result in serious toxicity in children.
Amiloxate
go.drugbank.com/drugs/DB11207ApprovedIt is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916].
Efinaconazole
go.drugbank.com/drugs/DB09040ApprovedInvestigationalEfinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis. … It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North America LLC under the name Jublia.
Betamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approved[A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.[A192444] … [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders.
Xanthinol
go.drugbank.com/drugs/DB09092ApprovedWithdrawn[L1080] It was approved as a drug in 1998 in Canada and nowadays its status is cancelled post marketing. … It is also known as xanthinol nicotinate.
Prednicarbate
go.drugbank.com/drugs/DB01130ApprovedIt is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. … Prednicarbate is a relatively new topical corticosteroid drug that displays a similar potency as [hydrocortisone].
Lorpiprazole
go.drugbank.com/drugs/DB09195ApprovedLorpiprazole is a serotonin antagonist and reuptake inhibitor used for the treatment of major depressive disorder. It is a piperazinyl-triazole derivative.
Birch bark extract
go.drugbank.com/drugs/DB16536ApprovedInvestigational(white birch), although hybrids of both species are used as well. … [L42390] Filsuvez was subsequently approved for the same indication by the US FDA in December 2023.
Triethylenetetramine
go.drugbank.com/drugs/DB06824ApprovedInvestigationalTETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925. … [L41730] TETA has been investigated in clinical trials for the treatment of heart failure in patients with diabetes.[A18804,A19332,A19333,A19334,A19335]
Faricimab
go.drugbank.com/drugs/DB15303ApprovedInvestigational[A225985, A225990, A225995, A226000, A226005, A226010] Faricimab was approved by the FDA on January 28, 2022, and is currently marketed under the trademark VABYSMO by Genentech, Inc. … [A225985, A225990, A225995] Vascular endothelial growth factor A (VEGF-A) is a well-known mediator of retinal NV, and many currently approved RVD therapies such as [aflibercept] and [ranibizumab] solely