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Displaying results 1081 - 1090 of 7452 in total
  1. Drug

    Ropeginterferon alfa-2b

    go.drugbank.com/drugs/DB15119
    ApprovedInvestigational

    [A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing and is not tolerated by all patients. … hemorrhage and thromboembolic events, and a long-term propensity for myelofibrosis and leukemia.

  2. Drug

    Zinc

    go.drugbank.com/drugs/DB01593
    ApprovedInvestigational

    Understanding the mechanisms that control brain zinc homeostasis is, therefore, imperative to the development of preventive and treatment regimens for these and other neurological disorders [A32465].

    Mixtures: For-2, Doctor's Choice Brand for MenCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  3. Drug

    Lanolin

    go.drugbank.com/drugs/DB11112
    Approved

    Lanolin primarily consists of long-chain waxy esters, or sterol esters, that lack glycerides. For this reason, it is also called wool wax or wool grease. … Lanolin is also frequently used in protective baby skin treatment and for sore nipples in breastfeeding mothers [L2583], [A32788].

    Mixtures: CVS A and D All-Purpose Skin Protectant, Kendra SKIN PROTECTION and PAIN RELIEF FOR HAIR REMOVALCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Nystatin

    go.drugbank.com/drugs/DB00646
    ApprovedInvestigationalVet approved

    Nystatin has a greater antifungal activity than amphotericin B - parenterally administered nystatin, however, is associated with significant toxicity and is not available in a formulation appropriate for … [A188562] As it undergoes very little absorption following oral or topical administration, nystatin's efficacy is limited to the treatment/prevention of cutaneous, mucocutaneous, and gastrointestinal fungal

    Categories: Antifungals for Topical Use, Antibacterials for Systemic Use
  5. Drug

    Palovarotene

    go.drugbank.com/drugs/DB05467
    Approved

    [A244920] Palovarotene was approved for use in Canada in January 2022 for the management of heterotopic ossification (HO) in patients with FOP, representing the first global approval for any FOP therapy … It first garnered interest as a potential treatment for emphysema but was eventually recognized as a potential novel therapy for patients with FOP.

  6. Drug

    Capsicum oleoresin

    go.drugbank.com/drugs/DB11131
    Approved

    to its analgesic properties, capsicum oleoresin is used to temporarily relieve of minor aches and pains of muscles and joints as an active ingredient in topical OTC preparations and has been studied for … The intensity of biological actions and toxicological effects of capsicum oleoresin are a direct function of the amount of capsaicinoids, or capsaicin, present in the compound [L1944].

    Mixtures: Arthricare for Women Ultra Strength, HO YAN HOR MEDICATED OIL
  7. Drug

    Pinaverium

    go.drugbank.com/drugs/DB09090
    ApprovedInvestigational

    Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. … It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable

    Categories: Drugs for Functional Gastrointestinal Disorders
  8. Drug

    Sulbactam

    go.drugbank.com/drugs/DB09324
    ApprovedInvestigational

    [L50131] When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.[A263296]

    Mixtures: SULBACTER POWDER FOR SOLUTION FOR INJECTION or INFUSION 3g/vial, SULBACTER POWDER FOR SOLUTION FOR INJECTION or INFUSION 1.5g/vialCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  9. Drug

    Flibanserin

    go.drugbank.com/drugs/DB04908
    ApprovedInvestigational

    Flibanserin is the first drug to be approved for hypoactive sexual desire disorder (HSDD) in premenopausal women by the FDA in August 2015. … In February of 2018 Flibanserin was approved by Health Canada under the brand name Addyi for a similar indication as approved by the FDA.

  10. Drug

    Pentobarbital

    go.drugbank.com/drugs/DB00312
    ApprovedVet approved

    It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration.