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Nitroprusside
go.drugbank.com/drugs/DB00325ApprovedInvestigationalNitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). … Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Categories: Nitrates and Nitrites, Indicators and ReagentsProducts: NITROPRUSIATO DE SODIO USP 25MG/ML, N-PRUSCarbopol 974P
go.drugbank.com/drugs/DB05384ApprovedWithdrawnIt was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies. … The compound, known as BufferGel, was in advanced clinical trials for its ability to prevent pregnancy, but was discontinued.
Products: LIQUIGEL UD 2.5MG/G EINZELUpadacitinib
go.drugbank.com/drugs/DB15091ApprovedInvestigationalIt is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage and bone destruction, leading to co-morbidities. … [L10896] In December 2019, it was additionally approved by the European Commission and Health Canada.[L10899,L42540] Upadacitinib is marketed under the brand name RINVOQ for oral administration.
Categories: Antineoplastic and Immunomodulating AgentsProducts: RINVOQ EXTENDED-RELEASE TABLET 15MG, RINVOQ 15mg Extended Release Film Coated TabletsNelfinavir
go.drugbank.com/drugs/DB00220ApprovedInvestigationalIt is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.
Products: Viracept -250mg, Viracept -50mgTrastuzumab
go.drugbank.com/drugs/DB00072ApprovedInvestigationalKanjinti (trastuzumab-anns)[L14135] and Hercessi[L52840] are other biosimilars approved by the FDA. In Canada, biosimilars ONTRUZANT[[L40303, L40308] and Adheroza[L52835] are approved. … Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and indirectly [A121].
Categories: Amino Acids, Peptides, and Proteins, pertuzumab and trastuzumabProducts: LICAR® POLVO LIOFILIZADO 150MG, LLICAR® POLVO LIOFILIZADO 150MGLevobupivacaine
go.drugbank.com/drugs/DB01002ApprovedInvestigationalWithdrawnto an anesthetic. … It is approximately 13 per cent less potent (by molarity) than racemic bupivacaine.Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal
Products: COZELTI ICEREN 10ML X 10 AMPUL, COZELTI ICEREN 10ML X 10 AMPULRumex acetosella pollen
go.drugbank.com/drugs/DB10359ApprovedRumex acetosella pollen is the pollen of the Rumex acetosella plant. Rumex acetosella pollen is mainly used in allergenic testing.
Categories: Non-Standardized Pollen Allergenic ExtractProducts: Pollens - Weeds and Garden Plants, Sorrel, Sheep Rumex acetosellaSotorasib
go.drugbank.com/drugs/DB15569ApprovedInvestigationalSotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen. … [A187550] Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s.[A235168] It is the first experimental KRAS inhibitor.
Categories: Antineoplastic and Immunomodulating AgentsProducts: LUMAKRAS FILM-COATED TABLET 120MGAcalabrutinib
go.drugbank.com/drugs/DB11703ApprovedInvestigationalor/and that fill an unmet medical need based on a surrogate endpoint. … [L42795,L42800] Unlike Calquence capsules, the co-administration of Calquence tablets and PPIs does not have an effect in the pharmacokinetics of acalabrutinib.
Categories: Antineoplastic and Immunomodulating AgentsProducts: CALQUENCE® 100MG, CALQUENCE HARD CAPSULES 100MGFerrous ascorbate
go.drugbank.com/drugs/DB14490ApprovedWithdrawnCategories: Diet, Food, and Nutrition, Blood and Blood Forming OrgansProducts: Ascofer Cap 275mg