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Grazoprevir
go.drugbank.com/drugs/DB11575ApprovedHCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. … of HCV infection is associated with significant long-term health benefits including reduced liver-related damage, improved quality of life, reduced incidence of Hepatocellular Carcinoma, and reduced all-cause
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseBenzylpenicilloyl polylysine
go.drugbank.com/drugs/DB00895ApprovedInvestigationalThe quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSecnidazole
go.drugbank.com/drugs/DB12834ApprovedInvestigational[A245503] Secnidazole has been available in many other countries in Europe, Asia, South America, and Africa for decades. … [A27210] Once it enters bacteria and parasites, secnidazole is activated by bacterial or parasitic enzymes to form a radical anion, thereby damaging and killing the target pathogen.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseRelapsed CD22-positive B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
go.drugbank.com/conditions/DBCOND0165828Drugs: Inotuzumab ozogamicinSynonyms: Relapsed CD22-positive B-cell Precursor Acute Lymphoblastic Leukemia (ALL)Loncastuximab tesirine
go.drugbank.com/drugs/DB16222ApprovedInvestigationalRelapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. … [L45206] This therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial.
Ferrous fumarate
go.drugbank.com/drugs/DB14491ApprovedInvestigationalUsed in treatment of iron deficiency anemia.
Mixtures: NUCLEVIT FOL, NUCLEVIT FOLNaloxegol
go.drugbank.com/drugs/DB09049ApprovedInvestigationalThe advantage of naloxegol over the opioid antagonist naloxone is that its PEGylated structure allows for high selectivity for peripheral opioid receptors and lack of entry into the central nervous system … Naloxegol, for "PEGylated naloxol" is a peripherally-selective opioid antagonist developed by AstraZeneca.
Categories: Drugs for Constipation, Heterocyclic Compounds with 4 or More RingsTropicamide
go.drugbank.com/drugs/DB00809Approved[A229958] It is also used in combination with [hydroxyamphetamine] for the same indication. … [A230103] Usually available in ophthalmic formulations, tropicamide is used to cause mydriasis and cycloplegia for eye exams or ocular procedures.
Efavirenz
go.drugbank.com/drugs/DB00625ApprovedInvestigationala high risk for HIV transmission. … For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: EFAVAX ® TABLETAS RECUBIERTAS POR 600MGTrolamine
go.drugbank.com/drugs/DB13747ApprovedInvestigationalTrolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine contains small amounts of diethanolamine and et...
Mixtures: Lecithin-aloe Moisture CreamCategories: Preparations for Treatment of Wounds and Ulcers