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Displaying results 1101 - 1110 of 10000 in total
  1. Drug

    Angiotensin II

    go.drugbank.com/drugs/DB11842
    ApprovedInvestigational

    The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin II to help maintain body blood pressure. … in adults with septic or other distributive shock.

    Synonyms: 5-L-isoleucineangiotensin II, 5-isoleucine-angiotensin IISalts: Angiotensin II acetate
  2. Drug

    Almotriptan

    go.drugbank.com/drugs/DB00918
    Approved

    Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. … It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that cause pain, nausea, and other symptoms

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesSynonyms: 1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidine
  3. Drug

    Dexketoprofen

    go.drugbank.com/drugs/DB09214
    ApprovedInvestigationalWithdrawn

    Dexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America. … It has analgesic, antipyretic and anti-inflammatory properties [L1298].

    International brands: KETRON D, FEN LIMixtures: Skudexa 75 mg/25 mg Granulat im Beutel zur Herstellung einer Lösung zum Einnehmen, VELIAN-B
  4. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine]. … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: AZITROMICINA MYLAN GENERICS, AZITROMICINA DOC GENERICI
  5. Drug

    Chlorpromazine

    go.drugbank.com/drugs/DB00477
    ApprovedInvestigationalVet approved

    Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup. … Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors.

    Categories: Dopamine D2 Receptor Antagonists, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine, 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine
  6. Indication

    Equinus Foot Deformity in Children With Cerebral Palsy

    go.drugbank.com/conditions/DBCOND0085039
    Drugs: Clostridium botulinum
    Synonyms: Equinus Foot Deformity in Children With Cerebral Palsy
  7. Indication

    Uncomplicated veins <1 mm in diameter Spider Veins

    go.drugbank.com/conditions/DBCOND0080571
    Drugs: Polidocanol
    Synonyms: Uncomplicated veins <1 mm in diameter Spider Veins, Uncomplicated veins <1 mm in diameter Spider vein
  8. Drug

    Flumazenil

    go.drugbank.com/drugs/DB01205
    ApprovedInvestigational

    Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine … receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingProducts: ANESED-R 1 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, ANESED-R 0.5 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET
  9. Drug

    Lacidipine

    go.drugbank.com/drugs/DB09236
    Approved

    It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce blood pressure. … Through radiotracer analysis, it was determined that lacidipine displays a high membrane partition coefficient leading to accumulation of the drug in the membrane and slow rate of membrane washout [A31539

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: LACIDIPINA DOC GENERICI, LACIPIL TABLET 4 mg
  10. Drug

    Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10769
    ApprovedInvestigational

    Synonyms: Japanese encephalitis virus strain SA 14-14-2 antigen (formaldehyde inactivated)Products: IXIARO Suspension for Injection 0.5ml in pre-filled syringe