Almotriptan

DB00918ApprovedSmall moleculeSelective Serotonin AgonistsSerotonin-1b and Serotonin-1d Receptor Agonist

Almotriptan is a 5-HT1B/1D receptor agonist used to treat migraines. Almotriptan is a triptan drug for the treatment of migraine headaches.

Chemical structure of Almotriptan
Mechanism
Curator reviewed
Primary indication
For the treatment of acute migraine headache in adultsCurator reviewed · 1 structured indication
Formula / weight
C17H25N3O2S · 335.464 g/mol (avg)
First approval
Canada, 2006 · United States, 2001
Code names
LAS-31416
Brand names
  • Axert

Resolves to

Compound
UNII1O4XL5SN61CAS154323-57-6ChEMBLCHEMBL1505ChEBI520985PubChem123606
Clinical / RWD
RxNorm279645ATCN02CC05PharmGKBPA10246
Structure
InChIKeyWKEMJKQOLOHJLZ-UHFFFAOYSA-NSMILESCN(C)CCC1=CNC2=C1C=C(CS(=O)(=O)N1CCCC1)C=C2
Targets
P30939HTR1FP28221HTR1DP28222HTR1B

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1,816Drug interactionsStructured to mechanism, not free text
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8Clinical trialsPhase, status and sponsor resolved per trial
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1Structured indicationCondition, population, route and combination as fields, not prose
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103Marketed productsAcross 4 countries and 26 labellers
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1ATC codeIncluding every combination product, plus 33 drug categories
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31+ReferencesStructured and connected to the statements they support
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