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Trimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalIt is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders [A19691].
Categories: Drugs for Functional Gastrointestinal Disorders, Cytochrome P-450 SubstratesProducts: DEBRIDAT FOR ORAL SUSPENSIONWitch hazel
go.drugbank.com/drugs/DB11111ApprovedInvestigationalNutraceuticalMixtures: Preparation H-PE Gel, PREPARATION H PE COOLING GELProducts: Pore Gone For Good, Preparation H for WomenBarzolvolimab
go.drugbank.com/drugs/DB18934InvestigationalBarzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)).
Synonyms: Immunoglobulin G1 [233-alanine,234-glutamine,251-tyrosine,253-threonine,255-glutamic acid,321-glutamine,de-C-terminal-lysine], anti-(human receptor tyrosine kinase KIT extracellular domain) (human-MusCaffeine
go.drugbank.com/drugs/DB00201ApprovedInvestigationalPremature birth can lead to apnea and bronchopulmonary dysplasia, a condition that interferes with lung development and may eventually cause asthma or early onset emphysema in those born prematurely. … [T716] The caffeine citrate injection, used for apnea of the premature newborn, was initially approved by the FDA in 1999.
Mixtures: PAT PO TJIN TJU SAN, Cold Remedy Gan Mao LingCategories: Tests for Gastric Secretion, Drugs for Obstructive Airway DiseasesEtigilimab
go.drugbank.com/drugs/DB18854InvestigationalEtigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).
Synonyms: Immunoglobulin g1, anti-(human receptor tigit(t-cell immunoreceptor with ig and itim domains)) (humanized mouse monoclonal omp-313m32 .gamma.1-chain), disulfide with humanized mouse monoclonal omp-313m32Serine
go.drugbank.com/drugs/DB00133ApprovedInvestigationalNutraceuticalA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.
Mixtures: Aminosyn-PF, Aminosyn-PFGlucarpidase
go.drugbank.com/drugs/DB08898ApprovedInvestigational[L39855] High-dose [methotrexate], an antifolate agent, has been widely and safely used for many decades in treating various cancers; however, even with aggressive hydration, urine alkalinization, and … for therapeutic purposes.
Categories: Detoxifying Agents for Antineoplastic TreatmentMethenamine
go.drugbank.com/drugs/DB06799ApprovedInvestigationalVet approvedIn salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Mixtures: UR N-C Urinary AntisepticCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseTazobactam
go.drugbank.com/drugs/DB01606ApprovedInvestigationalTazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. … It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections.
Mixtures: Aurotaz-P Powder for Injections 4.5 g, AUROTAZ-P 4.5 GCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseUlipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationalA recent systematic review proclaimed that the majority of available evidence demonstrates an inhibitory effect on ovulation rather than a post-fertilization effect on the endometrium, which has been heavily … Nevertheless, current and ongoing research into the agent's mechanism of action as an emergency contraceptive continue to provide potentially plausible evidence that ulipristal may, in fact, elicit activity
Categories: Hormonal Contraceptives for Systemic Use, Cytochrome P-450 Substrates