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Displaying results 1111 - 1120 of 3599 in total
  1. Target

    T cell receptor beta variable 6-5

    go.drugbank.com/bio_entities/BE0021562
    TargetHumans

    V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).

    Polypeptides: T cell receptor beta variable 6-5
  2. Drug

    CM4620

    go.drugbank.com/drugs/DB16466
    Investigational

    CM4620 (Zegocractin), is under investigation in multiple clinical trials, including NCT04195347 (pancreatitis due to asparaginase), NCT03709342 (PK/PD study in acute pancreatitis), NCT03401190 and NCT04681066

  3. Drug

    Pucotenlimab

    go.drugbank.com/drugs/DB17552
    ApprovedInvestigational

    Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours.

    Synonyms: Humanized pd-1 blocking antibody hx-008
  4. Drug

    Ursodeoxycholic acid

    go.drugbank.com/drugs/DB01586
    ApprovedInvestigational

    Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool. UDCA has been used to treat liver disease for decades: its first use in traditional me...

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Enzyme Inducers
  5. Drug

    Casimersen

    go.drugbank.com/drugs/DB14984
    ApprovedInvestigational

    [A218186] Casimersen is the most recent in a line of approved PMOs for treating DMD, including [eteplirsen] and [viltolarsen].

    Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
  6. Drug

    Nitazoxanide

    go.drugbank.com/drugs/DB00507
    ApprovedInvestigationalVet approved

    Nitazoxanide belongs to the class of drugs known as thiazolides. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular pro...

  7. Drug

    Lemborexant

    go.drugbank.com/drugs/DB11951
    ApprovedInvestigational

    [L10863] Recent research in the field of sleep disorders has revealed that insomnia is likely driven not by the inability of the brain to "switch on" sleep-related circuits, but rather an inability to … Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance.

    Categories: Orexin Receptor Antagonists, P-glycoprotein substrates
  8. Drug

    Magnesium Aluminum Silicate

    go.drugbank.com/drugs/DB11230
    ApprovedWithdrawn

    Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group . It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opac...

  9. Target

    High affinity immunoglobulin epsilon receptor subunit alpha

    go.drugbank.com/bio_entities/BE0000015
    TargetHumans

    High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells.

    Polypeptides: High affinity immunoglobulin epsilon receptor subunit alphaSynonyms: IgE Fc receptor subunit alpha
  10. Target

    High affinity immunoglobulin gamma Fc receptor I

    go.drugbank.com/bio_entities/BE0000710
    TargetCarrierHumans

    High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.

    Polypeptides: High affinity immunoglobulin gamma Fc receptor ISynonyms: IgG Fc receptor I