High affinity immunoglobulin gamma Fc receptor I

BE0000710ProteinHumansFCGR1A

High affinity receptor for the Fc region of immunoglobulins gamma. It is acted on by 16 drugs in DrugBank.

Gene name
FCGR1A
UniProtKB entry
P12314Swiss-Prot
Cellular location
Cell membrane
Residues / weight
374 residues · 42,632 Da
Also known as
Fc-gamma RI · Fc-gamma RIA · FCG1 · FcgammaRIa · FCGR1

Resolves to

Protein
UniProtP12314UniProt nameFCGR1_HUMAN
Gene
HGNCHGNC:3613NCBI Gene2209GenBank31332GeneCardsFCGR1A
Pharmacology
KEGGhsa:2209
Structure
PDB3RJDPDB4W4OPDB4X4M
Drugs

What you can answer from here — as of September 07, 2019

16DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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42+ReferencesStructured and connected to the statements they support
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Which approved drugs act on High affinity immunoglobulin gamma Fc receptor I, how selective are they, and which programs against it are still in active trials?

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