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Anagrelide
go.drugbank.com/drugs/DB00261ApprovedInvestigationalAnagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms. … [A214274] It appears to carry a better response rate than other thrombocythemia treatments (e.g. [busulfan], [hydroxyurea]) and may be better tolerated.[A214274]
Technetium Tc-99m disofenin
go.drugbank.com/drugs/DB09164ApprovedWithdrawnTechnetium Tc-99m is a metastable nuclear isomer and disofenin is an iminodiacetic acid derivative with no known pharmacologic actions at the doses recommended. … It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary
Peginterferon alfa-2a
go.drugbank.com/drugs/DB00008ApprovedInvestigationalPeginterferon alfa-2a is derived from the alfa-2a moeity of recombinant human interferon and acts by binding to human type 1 interferon receptors. … Peginterferon alfa-2a was used alongside [DB00811] with the intent to cure, or achieve a sustained virologic response (SVR), after 48 weeks of therapy.
Levacetylmethadol
go.drugbank.com/drugs/DB01227ApprovedWithdrawnLevacetylmethadol was withdrawn from use in the European Union due to its high risk of QT interval prolongation. The production of levacetylmethadol in the US has ceased as well.[L44052,T862]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeIsosorbide dinitrate
go.drugbank.com/drugs/DB00883ApprovedInvestigationalIts actions are similar to nitroglycerin but with a slower onset of action.
Tetrasul
go.drugbank.com/drugs/DB12838InvestigationalTetrasul has been used in trials studying the treatment of Erythematous (Type One) Rosacea.
Difelikefalin
go.drugbank.com/drugs/DB11938ApprovedInvestigational[A237610] These revelations led to the study of KOR agonists as a potential treatment option in patients suffering from pruritic conditions. … [A237620] Options for therapy are limited - with no FDA-approved treatments, off-label [gabapentin] was the most evidence-based and widely available treatment.
Calcium ascorbate
go.drugbank.com/drugs/DB14483ApprovedNutraceuticalMixtures: Formula F L W, Cavan OneEstradiol cypionate
go.drugbank.com/drugs/DB13954ApprovedVet approvedof hypoestrogenism due to hypogonadism [FDA Label]. … Esterification of estradiol aims to improve absorption and bioavailability after oral administration (such as with Estradiol Valerate) or to sustain release from depot intramuscular injections (such as
Tolazamide
go.drugbank.com/drugs/DB00839ApprovedA sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.