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CL-315585
go.drugbank.com/drugs/DB18758ExperimentalCL-315585 is the D isomer of Verteporfin.
Synonyms: Bpd-ma(sub d), Verteporfin-madDiethyltoluamide
go.drugbank.com/drugs/DB11282ApprovedDiethyltoluamide (DEET) is the common active ingredient in many insect repellent products. It is widely used to repel biting pests such as mosquitoes and ticks.
Obiltoxaximab
go.drugbank.com/drugs/DB05336ApprovedObiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin. … Obiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis toxin. It has an approximate molecular weight of 148 kDa.
Categories: Antiinfectives for Systemic UseDocusate
go.drugbank.com/drugs/DB11089ApprovedInvestigationalDocusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[A32201]. … Docusate can be orally or rectally administered. Docusate is on the World Health Organization's List of Essential Medicines[L5915].
Categories: Drugs for ConstipationThonzylamine
go.drugbank.com/drugs/DB11235ApprovedThonzylamine is an antihistamine and anticholinergic drug. … It is available as combination products with [DB04837] or [DB00388] for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.
Mixtures: Nasopen PE, Poly Hist PDCategories: Antihistamines for Topical Use, Antihistamines for Systemic UseMontelukast
go.drugbank.com/drugs/DB00471ApprovedInvestigationalMontelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. … [A178651] And although these kinds of effects are currently included in the official prescribing information for montelukast,[L6301,L6304,L6307,L6310,L6325,L6328,L6331] the drug still sees extensive use
Categories: Drugs for Obstructive Airway Diseases, Cytochrome P-450 SubstratesProducts: Mar-montelukast, MONK-PFamtozinameran
go.drugbank.com/drugs/DB17088ApprovedInvestigationalBA.4, BA.5) which, although similar, may behave differently from one another. … It is administered in combination with [tozinameran] for active immunization against COVID-19 caused by SARS-CoV-2, including infection caused by Omicron BA.4/BA.5.[L43907,L43912]
Capivasertib
go.drugbank.com/drugs/DB12218ApprovedInvestigationalTherefore, targeting the PIK3/AKT pathway presents a promising approach for the treatment of breast cancer, leading to the development of capivasertib, a pan-AKT kinase inhibitor. … [A262021,A262026,A262031] On November 17th, 2023, capivasertib, under the brand name TRUQAP, was approved by the FDA for the treatment of adult patients HR-positive, HER2-negative locally advanced or
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAnthralin
go.drugbank.com/drugs/DB11157ApprovedIt is a main active ingredient in topical skin formulations for the treatment of psoriasis. Various formulations of the drug are available, including solutions, foams, and shampoos [L1979]. … The chemical structure of anthralin allows for dual solubility, permitting the compound to be absorbed well through the epidermis [A27276].
Categories: Antipsoriatics for Topical UsePrasterone
go.drugbank.com/drugs/DB01708ApprovedInvestigationalNutraceuticalIn the United States, DHEA or DHEAS have been advertised with claims that they may be beneficial for a wide variety of ailments. … Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion.
Categories: Anabolic Agents for Systemic Use, Cytochrome P-450 Substrates