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Empagliflozin
go.drugbank.com/drugs/DB09038ApprovedInvestigationalin 2014. … Empagliflozin was further approved by the EMA in March 2022 and Health Canada in April 2022, making it the first and only approved treatment in Europe and Canada for adults with symptomatic chronic heart
Categories: Drugs Used in DiabetesAntithrombin Alfa
go.drugbank.com/drugs/DB11166ApprovedAntithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention of thromboembolic events in patients that have hereditary deficiency of antithrombin in high risk situations
Categories: Factor Xa InhibitorsDigoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigational[A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. … [L9143] This drug originates from the foxglove plant, also known as the _Digitalis_ plant[T610], studied by William Withering, an English physician and botanist in the 1780s.
Categories: Compounds used in a research, industrial, or household setting, BSEP/ABCB11 Substrates with a Narrow Therapeutic IndexAtezolizumab
go.drugbank.com/drugs/DB11595ApprovedInvestigationalAtezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers. … [L7489] Atezolizumab was granted FDA approval on 18 October 2016.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsJojoba oil
go.drugbank.com/drugs/DB14252ApprovedJojoba oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Anbiser B-HA Hyaluronic Acid Nourishing ConditionerCamizestrant
go.drugbank.com/drugs/DB19218ApprovedInvestigational[L64094,L64107] In pre- or peri-menopausal women and in men, camizestrant plus a CDK4/6 inhibitor is combined with an LHRH agonist or antagonist. … Camizestrant is an oral selective estrogen receptor degrader (SERD) and estrogen receptor (ER) antagonist used in combination with a CDK4/6 inhibitor to treat hormone receptor-positive, HER2-negative locally
Synonyms: 3-pyridinamine, n-(1-(3-fluoropropyl)-3-azetidinyl)-6-((6s,8r)-6,7,8,9-tetrahydro-8-methyl-7-(2,2,2-trifluoroethyl)-3h-pyrazolo(4,3-f)isoquinolin-6-yl)-, N-(1-(3-fluoropropyl)-3-azetidinyl)-6-((6s,8r)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3h-pyrazolo(4,3-f)isoquinolin-6-yl)-3-pyridinamineRumex crispus whole
go.drugbank.com/drugs/DB14267ApprovedRumex crispus whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Herborex Fort Lax LiqProducts: JEUNCELL a drug for atopic dermatitisDiamorphine
go.drugbank.com/drugs/DB01452ApprovedIllicitDiamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. … As heroin, it is illegal to manufacture, possess, or sell in the United States and the UK. However, under the name diamorphine, heroin is a legal prescription drug in the United Kingdom.
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersMelatonin
go.drugbank.com/drugs/DB01065ApprovedInvestigationalNutraceuticalVet approvedReduced melatonin production has also been proposed as a likely factor in the significantly higher cancer rates in night workers. … The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence the name), that is located in the center of the brain (rostro-dorsal to the superior colliculus
Categories: Compounds used in a research, industrial, or household settingSynonyms: 5-methoxy-N-acetyl tryptamine, 5-methoxy-N-acetyltryptamineCasimersen
go.drugbank.com/drugs/DB14984ApprovedInvestigational[A218186] Casimersen is the most recent in a line of approved PMOs for treating DMD, including [eteplirsen] and [viltolarsen]. … [A218186, L32118] In this manner, PMOs are much less susceptible to endo- and exonucleases and exhibit drastically reduced metabolic degradation compared to traditional synthetic oligonucleotides.
Categories: Compounds used in a research, industrial, or household setting