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Antithrombin Alfa is a recombinant antithrombin used to treat peri-operative and peripartum thromboembolic events in hereditary antithrombin deficiency. A medication used to prevent unwanted blood clotting in labor, delivery, and surgery in patients with low levels of antithrombin.
- Mechanism
- Curator reviewed
Antithrombin is the main inhibitor of thrombin and Factor Xa, the serine proteases involved in blood coagulation. Antithrombin neutralizes the activity of thrombin and Factor Xa by forming a complex which is rapidly removed from the circulation.
- Primary indication
- Antithrombin alfa is a recombinant antithrombin it is indicated for the prevention of peri-operative and peri-partum thromboembolic events in patients with hereditary deficiency of antithrombin.Curator reviewed · 2 structured indications
- First approval
- United States, 2009
- Also known as
- Antithrombin (recombinant) · Antithrombin III, recombinant · Antithrombin III,recombinant
- Code names
- KW-3357
- Brand names
- Atryn
Resolves to
What you can answer from here — as of March 06, 2025
Which drugs share a target with Antithrombin Alfa, and which of those have an active Phase 3 trial?