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Atazanavir
go.drugbank.com/drugs/DB01072ApprovedInvestigationalFood and Drug Administration (FDA) approved atazanavir on June 20, 2003. … Atazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day) and has lesser effects on the patient's lipid profile (the amounts of cholesterol
Categories: Heterocyclic Compounds, 1-Ring, Antivirals for Systemic UseProducts: VIRAZAN® 150 MG, TAVIRAPIN 150 MGBosutinib
go.drugbank.com/drugs/DB06616ApprovedInvestigationalBosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive … [A6901,A17961] Bosutinib was first approved by the FDA in 2012 for the treatment of adult chronic, accelerated, or blast-phase Ph+ CML with resistance or intolerance to prior therapy.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrileEplerenone
go.drugbank.com/drugs/DB00700ApprovedInvestigationalEplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone ...
Categories: Antihypertensive Agents Indicated for HypertensionProducts: EPLERENON 1A PHARMA 25MG, EPLERENON 1A PHARMA 50MGAnidulafungin
go.drugbank.com/drugs/DB00362ApprovedThere is preliminary evidence that it has a similar safety profile to caspofungin. … Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366.
Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseProducts: GIXOFU 100 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, ANIDACCORD 100 POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100 MGSelenium
go.drugbank.com/drugs/DB11135ApprovedInvestigationalVet approvedSelenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen
Mixtures: PreQue 10, PreQue 10Categories: Compounds used in a research, industrial, or household settingAsunaprevir
go.drugbank.com/drugs/DB11586ApprovedWithdrawnIt has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b. … The commercialization of asunaprevir was cancelled one year later on October 16, 2017.[L1113]
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: SUNVEPRA 100 MG KAPSÜL, 56 ADETRilpivirine
go.drugbank.com/drugs/DB08864ApprovedInvestigationalRilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients.[A31328] It is a diarylpyrimidine derivative. … [L31193] While previously administered once-monthly only, this combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and without the need for an oral lead-in
Mixtures: ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 90 ADET, ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 30 ADETCategories: Heterocyclic Compounds, 1-Ring, Antivirals for Systemic UseNystatin
go.drugbank.com/drugs/DB00646ApprovedInvestigationalVet approvedfor systemic use. … Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably _Candida_ species.
Mixtures: NİFUNİS 500 MG/200.000 I.U. VAJİNAL OVÜL, 12 ADET, NİFUNİS 500 MG/200.000 I.U. VAJİNAL OVÜL, 6 ADETCategories: Compounds used in a research, industrial, or household setting, Antifungals for Topical UseOxymetholone
go.drugbank.com/drugs/DB06412ApprovedIllicitOxymetholone is a synthetic anabolic steroid marketed under the brand name Anapolon by Hoffmann La Roche Limitedand used in the treatment of osteoporosis, anaemia, and as an agent to stimulate muscle growth … in malnourished or underdeveloped patients.
Categories: Anabolic Agents for Systemic UseProducts: ANAPOLON 50 MG TABLET, 30 ADET, ANAPOLON 50 MG TABLET, 90 ADETBortezomib
go.drugbank.com/drugs/DB00188ApprovedInvestigationalBortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. … [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide, [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid