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Moxisylyte
go.drugbank.com/drugs/DB09205Approved[L1172] This drug was developed by the Japanese company Fujirebio and also by the American company Iolab in the late 80s. … [T45] According to the WHO, moxisylyte is approved since 1987[T91] and in the same year, it acquired the denomination of orphan product by the FDA.
Pleconaril
go.drugbank.com/drugs/DB05105InvestigationalIt acts by inhibiting viral replication. The use of pleconaril has not gained approval by the U.S. … Pleconaril is an antiviral drug from _viral capsid inhibitor_ class, manufactured by _Schering-Plough_ and intended for the prevention of acute asthma exacerbations and common cold symptoms in asthmatic
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseFludeoxyglucose (18F)
go.drugbank.com/drugs/DB09502ApprovedInvestigationalIt is administered by intravenous injection.
Levonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigationalLevonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy. Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released fr...
Categories: Hormonal Contraceptives for Systemic UseProducts: ONIVE 1® 1.5 MG TABLETA, ONIVE 2® 0.75 MG TABLETASAloe vera leaf
go.drugbank.com/drugs/DB13906ApprovedInvestigationalThe use of aloe vera in constipation, inflammatory disorders, cancer, ulcer, and diabetes has also been investigated [A32476]. … Acemannan and other modified polysaccharides are responsible in preventing suppression of contact hypersensitivity or immune suppression induced by external factors such as irradiation [A32473].
Cromoglicic acid
go.drugbank.com/drugs/DB01003ApprovedInvestigationalIt is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack. … A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.
Benzylpenicilloyl polylysine
go.drugbank.com/drugs/DB00895ApprovedInvestigationalBenzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy. The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a us...
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseEdoxudine
go.drugbank.com/drugs/DB13421ApprovedWithdrawn[A32643] It was developed by McNeil Pharmaceutical and approved by Health Canada on December 31, 1992. This medication was later discontinued from the market in 1998.[L1113] … It was later recognized to be effective in vivo in a preclinical model of keratitis caused by herpes virus.
Foreskin keratinocyte (neonatal)
go.drugbank.com/drugs/DB10772ApprovedOrcel, another skin substitute, is similar to Apligraf since it contains both fibroblasts and keratinocytes derived from neonatal foreskin, but in addition, utilizes a type I collagen sponge as its matrix … Apligraf has been useful in the treatment of venous leg ulcers and diabetic foot ulcers, by increasing rates of wound healing and decreasing the time required for closure of wounds [L2452].
Omaveloxolone
go.drugbank.com/drugs/DB12513ApprovedInvestigationalTherefore, the use of Nrf2 activators such as omaveloxolone represents a therapeutic advantage in this group of patients. … [L51654], [L52595] The use of omaveloxolone for the treatment of conditions involving mitochondrial dysfunction and oxidative stress has also been evaluated.[A257534,A257559]