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Semaglutide
go.drugbank.com/drugs/DB13928ApprovedInvestigationalSemaglutide works by binding to and activating the GLP-1 receptor, thereby stimulating insulin secretion and reducing blood glucose. … [A31421,L8681] Other members of this drug class include [Exenatide] and [Liraglutide]. Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection in December 2017.
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsProducts: Rybelsus 14mg Tablet, RYBELSUS® TABLET 14MGSarilumab
go.drugbank.com/drugs/DB11767ApprovedInvestigational[A27262] Sarilumab was developed by Sanofi and Regeneron Pharmaceuticals, Inc; it was US FDA-approved in May 2017 and followed by EU approval in June 2017 for the treatment of moderate to severe rheumatoid … [A27265] RA is a chronic inflammatory disease characterized by polyarthritis, and its treatment has been challenged by the different responses in every patient.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: KEVZARA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 150MG, KEVZARA Solution for Injection in Pre-filled Pen 150mgHeparin
go.drugbank.com/drugs/DB01109ApprovedInvestigationalIt binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. … Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
Mixtures: Heparin Sod and 0.9% Sod Chloride Inj, Heparin Sodium and Dextrose 5% Inj USPCategories: Heparin and similars, Blood and Blood Forming OrgansOxyphenbutazone
go.drugbank.com/drugs/DB03585ApprovedWithdrawnOxyphenbutazone was withdrawn from the Canadian market in March 1985 due to concerns regarding bone marrow suppression.
Categories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Antiinflammatory and Antirheumatic ProductsProducts: Oxybutazone Tab 100mg, Oxyphenbutazone 100mg TabletsPenicillium chrysogenum var. chrysogenum
go.drugbank.com/drugs/DB10439ApprovedPenicillium chrysogenum var. chrysogenum is a fungus which can provoke allergic reactions. Penicillium chrysogenum var. chrysogenum extract is used in allergenic testing.
Categories: Non-Standardized Fungal Allergenic ExtractProducts: Molds, Rusts and Smuts, Penicillium notatumCholic Acid
go.drugbank.com/drugs/DB02659ApprovedInvestigational[PubChem] Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid synthesis disorders due to single … A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
Categories: Bile Acids and Salts, Bile and Liver TherapyProducts: CHOLBAM® 250MG, CHOLBAM® 50MGAmaranthus retroflexus pollen
go.drugbank.com/drugs/DB10381ApprovedAmaranthus retroflexus pollen is the pollen of the Amaranthus retroflexus plant. Amaranthus retroflexus pollen is mainly used in allergenic testing.
Categories: Non-Standardized Pollen Allergenic ExtractProducts: Pollens - Weeds and Garden Plants, Pigweed, Rough Redroot Amaranthus retroflexusDisulfiram
go.drugbank.com/drugs/DB00822ApprovedInvestigationalA carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. … and other symptoms (acetaldehyde syndrome).
Categories: Scabicides, Insecticides and Repellents, Antiparasitic Products, Insecticides and RepellentsSynonyms: N,N,N',N'-tetraethylthiuram disulfide, 1,1'-dithiobis(N,N-diethylthioformamide)Rasagiline
go.drugbank.com/drugs/DB01367ApprovedInvestigationalRasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: (1R)-N-propargylindan-1-amine, (R)-N-2-Propynyl-1-indanamineTafamidis
go.drugbank.com/drugs/DB11644ApprovedInvestigationalTafamidis and tafamidis meglumine (FX-1006A) are benzoxazole derivatives[A27206] developed by FoldRX.[A189717] Tafamidis is structurally similar to diflusinal. … [A189717] Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 May 2019.[L11280]
Categories: Hormones, Hormone Substitutes, and Hormone AntagonistsProducts: VYNDAQEL SOFT GELATIN CAPSULE 20MG