Search

Displaying results 1141 - 1150 of 10000 in total
  1. Target

    Glutamine synthetase 1

    go.drugbank.com/bio_entities/BE0002555
    TargetMycobacterium tuberculosis

    Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia (PubMed:12819079, PubMed:7937767). Also able to use GTP (PubMed:7937767). D-glutamate is a poor s...

    Synonyms: Glutamine synthetase I beta, Glutamine synthetase I beta
  2. Drug

    Cultivated mushroom

    go.drugbank.com/drugs/DB10544
    Approved

    Cultivated mushroom allergenic extract is used in allergenic testing.

    Synonyms: Agaricus bisporus (mushroom) cap/stem extractCategories: Non-Standardized Food Allergenic Extract
  3. Drug

    Tralokinumab

    go.drugbank.com/drugs/DB12169
    ApprovedInvestigational

    It neutralizes IL-13 activity by inhibiting its ability to bind with receptors, thus helping to alleviate AD symptoms. … US in December 2021.

  4. Drug

    Calcium carbimide

    go.drugbank.com/drugs/DB09116
    ApprovedWithdrawn

    Its effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic product acetaldehyde. … Calcium carbimide was conceived as an alternative for the treatment of alcoholism with a reduced side effect profile either when it is consumed accompanied by alcohol or without it.

    Categories: Drugs Used in Addictive Disorders, Drugs Used in Alcohol DependenceSynonyms: Cyanamide, calcium salt (1:1), methanediimine, calcium salt (1:1)
  5. Indication

    Familial periodic paralysis

    go.drugbank.com/conditions/DBCOND0008063
    Drugs: Acetazolamide
    Synonyms: Periodic paralysis I
  6. Drug

    Flupentixol

    go.drugbank.com/drugs/DB00875
    ApprovedInvestigationalWithdrawn

    It is approved for use in Canada and other countries around the world, but not in the US. … Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein inhibitorsProducts: Fluanxol Depot 2% -liq Im 20mg/ml, FLUANXOL DEPOT 20MG/ML IM ENJ. SOLUSYON, 1 ADET
  7. Drug

    Carbon monoxide

    go.drugbank.com/drugs/DB11588
    ApprovedInvestigational

    Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than air. … The DLCO measures the ability of the lungs to transfer gas from inhaled air to the red blood cells in pulmonary capillaries. The DLCO test is both convenient and simple for the patient to undergo.

    Synonyms: carbon(II) oxide, COMixtures: Lung Diffusion Test Mix No Ne Co, Co-NE-O2-N2 Mixture
  8. Drug

    Hydroxyprogesterone caproate

    go.drugbank.com/drugs/DB06789
    Approved

    In April 2023, the FDA withdrew its approval of Makena and its generics given an unfavorable risk-to-benefit assessment.[L46113] … Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S.

    Synonyms: 17alpha-Caproyloxypregn-4-ene-3,20-dioneMixtures: GRAVIDINONA 2 ML
  9. Drug

    Inclisiran

    go.drugbank.com/drugs/DB14901
    ApprovedInvestigational

    By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma concentrations of LDL cholesterol. … [L28178] Inclisiran was later approved by the FDA on December 22, 2021, for the treatment of heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease in adults

    Categories: Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia, Compounds used in a research, industrial, or household settingProducts: LEQVIO SOLUTION FOR INJECTION IN PREFILLED SYRINGE 284 MG/1.5 ML, Sybrava 284mg/1.5ml Solution for Injection in Pre-filled Syringe
  10. Drug

    Domperidone

    go.drugbank.com/drugs/DB01184
    ApprovedInvestigationalVet approved

    A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.

    Synonyms: 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one, 5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinoneCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates