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Dexchlorpheniramine maleate
go.drugbank.com/drugs/DB09555ApprovedDexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture.
Mixtures: Rescon MX, HUFADEXTA-MCategories: Heterocyclic Compounds, 1-RingZolmitriptan
go.drugbank.com/drugs/DB00315ApprovedInvestigational[A193797] Zolmitriptan was first approved by the FDA for sale by Zeneca Pharmaceuticals under the trade name Zomig® on November 25, 1997. … Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine.
Synonyms: 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one, (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-oneCategories: Heterocyclic Compounds, 2-Ring, Serotonin-1b and Serotonin-1d Receptor AgonistEtidronic acid
go.drugbank.com/drugs/DB01077ApprovedInvestigational[A203111] Etidronic acid was granted FDA approval on 1 September 1977.[L13901] … [A1923] Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]
Synonyms: (1-Hydroxyethylidene)bis(phosphonic acid), 1-Hydroxy-1,1-diphosphonoethaneProducts: DIDRONAT 200 MG TABLET, 60 ADET, DIDRONAT 400 MG TABLET, 30 ADETEntecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalIt is marketed under the trade name Baraclude (BMS). … It was approved by the U.S. Food and Drug Administration (FDA) in March 2005.
Categories: Heterocyclic Compounds, 2-RingProducts: HEPATOVIR-B 0.05 MG/ML ORAL ÇÖZELTİ, 210 ML, OVAMET 1 MG FILM KAPLI TABLET,30 ADETSimeprevir
go.drugbank.com/drugs/DB06290ApprovedWithdrawnThe SVR12 was 83% (29/35) in treatment-naïve patients and 86% (19/22) in relapsing patients. … The overall SVR12 was 88% (44/50) in treatment-naïve patients with cirrhosis [L852].
Products: OLYSIO 150 MG KAPSUL ,KAPSUL, 28 ADETIsavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalAs isavuconazole displays low water solubility, it is found as an active ingredient of its prodrug, [DB06636]. … Resistance to isavuconazole has been associated with the mutation in the target gene CYP51 [FDA Label].
Categories: Heterocyclic Compounds, 1-RingProducts: CRESEMBA (100 MG HARD CAPSULES), CRESEMBA (POWDER FOR SOLUTION FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200 MG/VIAL)Fedratinib
go.drugbank.com/drugs/DB12500ApprovedInvestigational[A183188] Fedratinib was granted FDA approval on August 16, 2019.[L8090] … Fedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis.
Categories: MATE 2 Inhibitors, MATE 1 InhibitorsProducts: Inrebic 100 mg Sert Kapsül, 120 ADET, Inrebic 100 mg capsulesDesipramine
go.drugbank.com/drugs/DB01151ApprovedTCAs also block histamine-H<sub>1</sub> receptors, α<sub>1</sub>-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred … Secondary amine TCAs, such as desipramine and nortriptyline, are more potent inhibitors of norepinephrine reuptake than tertiary amine TCAs, such as amitriptyline and doxepine.
Products: DESIPRAM 25 MG TABLET, 100 ADET, Desipramine-10 - Tab 10mgCinacalcet
go.drugbank.com/drugs/DB01012ApprovedInvestigationalCinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe.
Synonyms: N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine, (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amineProducts: MIMPARA® 60 MG, VISCAP 30 MG FILM TABLET, 28 ADETOmalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigational[A39518] Omalizumab was first approved in the US in 2003 [A263507] and in Europe in 2005.
Products: XOLAIR ® 150 MG, XOLAIR 150 MG/ML ENJEKSIYONLUK COZELTI İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET