Search
Palbociclib
go.drugbank.com/drugs/DB09073ApprovedInvestigationalPalbociclib is a piperazine pyridopyrimidine[A176792] that acts in the cell cycle machinery. … [L5867] It was originally FDA approved on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and its indications were updated in April 2019 to include male
Synonyms: 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-8h-pyrido(2,3-d)pyrimidin-7-one, 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-oneProducts: REAMPLA 100 MG KAPSÜL, 21 KAPSÜL, REAMPLA 100 MG FİLM KAPLI TABLET, 21 ADETLevodropropizine
go.drugbank.com/drugs/DB12472InvestigationalLevodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
Mixtures: PULMOTUS 30 MG+ 2 MG/5 ML ŞURUP, 150 ML, DROPOLEV ŞURUP ,150 MLProducts: LEVOPRONT 60 MG TABLET, 20 ADET, LEVOPRONT SYRUP 60 mg/10 mlPalonosetron
go.drugbank.com/drugs/DB00377ApprovedInvestigationalIt is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of … Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
Synonyms: 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one, (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-oneCategories: Heterocyclic Compounds, 2-RingSulbactam
go.drugbank.com/drugs/DB09324ApprovedInvestigational[L50131] When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.[A263296]
Mixtures: BACTAMED 500 MG/250 MG IM IV ENJEKTABL TOZ IÇEREN FLAKON, 10 ADET, AMPİSİD 500 MG/250 MG IM ENJEKSİYONLUK TOZ, 1 ADETCategories: Heterocyclic Compounds, 2-RingChlorpropamide
go.drugbank.com/drugs/DB00672ApprovedWithdrawnUp to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites. … Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor.
Synonyms: 1-(p-chlorobenzenesulfonyl)-3-propylurea, 1-(p-chlorophenylsulfonyl)-3-propylureaCategories: Drugs Used in DiabetesTemsirolimus
go.drugbank.com/drugs/DB06287ApprovedInvestigationalTemsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007. … Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel.
Products: TORISEL 25 MG/ML IV INFUZYONLUK COZELTI ICEREN FLAKON, 1 ADET, TORISEL ® 30 MGCONCENTRADO PARA SOLUCION PARA INYECCION(25 MG/ML)Palivizumab
go.drugbank.com/drugs/DB00110ApprovedInvestigationalPalivizumab is expressed from a stable murine (mouse) myeloma cell line (NS0). … Palivizumab is composed of to heavy chains (50.6 kDa each) and two light chains (27.6 kDa each), contains 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF)
Products: SYNAGIS® 50 MG, SYNAGIS 50 MG/0.5 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADETGalectin-10
go.drugbank.com/bio_entities/BE0001886TargetHumansRegulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg)
Polypeptides: Galectin-10Synonyms: Gal-10Frizzled-10
go.drugbank.com/bio_entities/BE0020969TargetHumansReceptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclea...
Polypeptides: Frizzled-10Synonyms: Fz-10Colchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigationalColchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961. … [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602]
Categories: Experimental Unapproved Treatments for COVID-19, Preparations With No Effect on Uric Acid MetabolismProducts: KOLSIN 0.5 MG FİLM KAPLI TABLET,60 ADET, COLCHICUM DISPERT 0,5 MG FILM TABLET, 50 ADET