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Sodium oxybate
go.drugbank.com/drugs/DB09072ApprovedInvestigationalSodium oxybate has been misused to stimulate body growth and to induce euphoria, disinhibition, and sexual arousal as a "party drug" or "club drug." … [A251430] Due to its physiological effects, sodium oxybate is associated with a risk for substance misuse and abuse.
Products: Natriumoxybat Kalceks 500 mg/ml Lösung zum Einnehmen, Natriumoxybat neuraxpharm 500 mg/ml Lösung zum EinnehmenFluocinolone acetonide
go.drugbank.com/drugs/DB00591ApprovedInvestigationalVet approvedFluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a corticosteroid that presents a high lipophilicity. … [T358] This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and approved by FDA in May 2016.[L4676]
Synonyms: 6α,9α-difluoro-16α-hydroxyprednisolone 16,17-acetonideInternational brands: Co-FIuosinPerphenazine
go.drugbank.com/drugs/DB00850ApprovedInvestigationalAn antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Mixtures: โพลีบอน 4-10, Etrafon 2 10Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesLevosimendan
go.drugbank.com/drugs/DB00922ApprovedInvestigationalWithdrawnLevosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. … It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels. Levosimendan is used to manage acutely decompensated congestive heart failure.
Products: SIMDAX 2.5 MG/ML KONSANTRE INF.COZ.5 ML X FLAKON, 1 ADET, SİMELEV 12,5 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETEdetate calcium disodium anhydrous
go.drugbank.com/drugs/DB14598ApprovedInvestigational[A204173] Edetate calcium disodium was granted FDA approval on 16 July 1953.[L12774] … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: LIBENTA AMPUL 2ML, 10 ADET, LIBENTA AMPUL 2ML, 100 ADETEsketamine
go.drugbank.com/drugs/DB11823ApprovedInvestigational[L5596,A175462] On March 5, 2019, the nasal spray drug, _esketamine_, also known as _Spravato_ (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. … The intranasal route of administration for this drug allows for easy administration and a fast onset of action, which sets it apart from many other antidepressant agents that may take several weeks to
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanoneHyaluronidase
go.drugbank.com/drugs/DB14740ApprovedInvestigational[A199026] Hyaluronidase has been used in surgical settings for at least the past 60 years to improve the diffusion of local anesthetics. … Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents.
Products: Wydase Injection Liq 150 Units/ml, ไฮลาเชฟ 150 ไอ.ยู.Nirsevimab
go.drugbank.com/drugs/DB16258ApprovedInvestigational[A254691] This is due to a modification in the Fc region of nirsevimab that grants it a longer half-time compared to typical monoclonal antibodies. … [L44146] Nirsevimab was also approved by Health Canada on April 19, 2023 and by the FDA in July 17, 2023 for the same indication.[L46392,L47461]
Synonyms: Immunoglobulin g1-kappa, anti-(human respiratory syncytial virus fusion glycoprotein f0 (protein f))human monoclonal antibody.gamma.1 heavy chain (1-456) (human vh (homo sapiens ighv1-69*01(ighd)-ighj4Products: Beyfortus 50 mg Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 5 adet, iğnesiz, Beyfortus 50 mg Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 1 adet, iğnesizNicergoline
go.drugbank.com/drugs/DB00699ApprovedIt has been suggested to ameliorate cognitive deficits in cerebrovascular disease.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: 10-methoxy-1,6-dimethylergoline-8β-methanol 5-bromonicotinate, (8β)-10-methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridinecarboxylate (ester)Flutemetamol (18F)
go.drugbank.com/drugs/DB09151ApprovedInvestigationalIt is used to evaluate Alzheimer's disease (AD) or other causes of cognitive decline as an Aβ-specific positron emission tomography (PET) ligand.[L35029] … Flutemetamol (18F), an analogue of [(11)C]PIB,[A18519] is a radioactive diagnostic drug used for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic plaque density.
Products: VİZAMYL 150 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ML