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Tocopherol
go.drugbank.com/drugs/DB11251ApprovedInvestigational[A32436] It is currently under the list of substances generally recognized as safe (GRAS) in the FDA for the use of human consumption.[L2114] … Tocopherol exists in four different forms designated as α, β, δ, and γ. They present strong antioxidant activities, and it is determined as the major form of vitamin E.
Categories: Compounds used in a research, industrial, or household settingEnzacamene
go.drugbank.com/drugs/DB11219ApprovedIt is used in cosmetic products such as sunscreen to provide skin protection against UV rays. … While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and cosmetic products is approved by Health Canada.
Mixtures: Outback 2-in-1 Insect Repellent and Protective SunscreenPotassium bicarbonate
go.drugbank.com/drugs/DB11098ApprovedInvestigationalIt is used in medicine as an antacid.[T141] It is registered in the FDA under the section of suitable, safe and effective ingredients for OTC antacids. … Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution.
Mixtures: Multi-min Electro C Pow Plus B2Acetrizoic acid
go.drugbank.com/drugs/DB09347ApprovedWithdrawn[A32135] It was first synthesized by Wallingford in 1953[A32136] and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th, 1978. … [L1704] Acetrizoic acid presents, in the FDA records, a category of drug substance with an inactive status.[L1703]
Categories: Compounds used in a research, industrial, or household settingGadoteridol
go.drugbank.com/drugs/DB00597ApprovedInvestigationalgadolinium in the brain. … [A263076] Initially approved by the FDA in 1992, gadoteridol received additional approval in 2020 for use in pediatric patients less than 2 years old.[L49876]
Categories: Compounds used in a research, industrial, or household settingAfamelanotide
go.drugbank.com/drugs/DB04931ApprovedFDA approval in October 2019. … [A187202,A187205] Afamelanotide is currently the only approved drug therapy used in the management of erythropoietic protoporphyria, having received approval in the EU in December 2014[L9119] and subsequent
Synonyms: MT-I, Melanotan ICategories: Compounds used in a research, industrial, or household settingNalmefene
go.drugbank.com/drugs/DB06230ApprovedInvestigationalWithdrawn[L1024] In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. … [L1024] Nalmefene was approved in the United States in 1995 as an antidote for opioid overdose.[A245839] Nalmefene injection is used to manage known or suspected opioid overdose.
Categories: Drugs Used in Alcohol Dependence, Drugs Used in Addictive DisordersBronopol
go.drugbank.com/drugs/DB13960ApprovedFirst synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives … L4873] and in other products where it may not primarily be used in the role of a non-medicinal preservative antimicrobial [L4874].
Categories: Compounds used in a research, industrial, or household settingTelmisartan
go.drugbank.com/drugs/DB00966ApprovedInvestigationalTelmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. … smooth muscle, ultimately leading to a reduction in arterial blood pressure.
Categories: Angiotensin II receptor antagonists, Angiotensin II Type 1 Receptor BlockersQuetiapine
go.drugbank.com/drugs/DB01224ApprovedInvestigationalInitially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. … It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189]
Products: FRENI-S IR, Q-PIN