DB11098ApprovedInvestigationalSmall molecule
Potassium bicarbonate is an ingredient used as an antacid or to treat hypokalemia. Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance.
- Mechanism
- Curator reviewed · 2 references
The antacid potential of potassium bicarbonate is attained by increasing the gastrointestinal pH by neutralizing hydrochloric acid. The increase in pH results in suppression of the action of pepsin which is the enzyme that exacerbates ulceration due to the presence of acid.
- Primary indication
- Potassium bicarbonate is used as an antacid, electrolyte replenisher and potassium supplement.Curator reviewed · 11 structured indications
- Formula / weight
- CHKO3 · 100.1151 g/mol (avg)
- First approval
- Canada, 1996 · European Union, 2021
- Also known as
- Potassium hydrogen carbonate
- Code names
- ADV7103-BK · E-501(II) · INS-501(II) · INS NO.501(II)
- Brand names
Resolves to
Clinical / RWD
Structure
InChIKey
TYJJADVDDVDEDZ-UHFFFAOYSA-MSMILES[K+].OC([O-])=OTransporters
What you can answer from here — as of May 26, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
2TransportersSubstrate / inhibitor direction, not just membershipListed above
Which other approved drugs treat the same conditions as Potassium bicarbonate, and which companies have late-stage candidates in those indications?
Create a free account or log in to explore the full data card.
Create Account