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Bemiparin Action Pathway
smpdb.ca/view/SMP0126156Drug actionSome precautions is that Bemiparin may suppress the adrenal secretion of aldosterone and lead to elevated potassium. … It is excreted through hepatic and renal routes, elimination of the drug is impaired if there are issues with the renal or hepatic systems.
Drugs: CalciumEnzymes: Antithrombin-IIISulodexide Action Pathway
smpdb.ca/view/SMP0126173Drug actionIts mechanism of action inhibits coagulation by inhibiting antithrombin III thus stopping the conversion of prothrombin and thrombin. … It is eliminated through renal, fecal and bile routes, and sometimes adverse effects occur that relate to the gastrointestinal system.
Drugs: CalciumEnzymes: Antithrombin-IIIReviparin Action Pathway
smpdb.ca/view/SMP0126278Drug actionReviparin is a low molecular weight heparin derived from a pig's intestinal mucus and used to prevent thromboembolism.
Enzymes: Antithrombin-IIIArdeparin Action Pathway (new)
smpdb.ca/view/SMP0126657Drug actionArdeparin acts on antithrombin III, which leads to the inactivation of factor Xa and thrombin inhibiting thrombosis. It is administered subcutaneously and travels to its target in the bloodstream. … Due to its anticoagulant nature herbs and supplements with similar activity should be avoided such as ginseng, ginkgo, ginger and garlic.
Enzymes: Antithrombin-IIIAxitinib Action Pathway
smpdb.ca/view/SMP0126901Drug actionAxitinib is recognized for its high potency compared to earlier VEGFR inhibitors and is available in oral formulations under the brand name Inlyta®. … By blocking these receptors, axitinib hinders the process of angiogenesis (formation of new blood vessels), which is crucial for tumor growth and metastasis.
Enzymes: Antithrombin-IIICabozantinib Action Pathway
smpdb.ca/view/SMP0126903Drug actionCabozantinib's mechanism of action involves inhibiting various receptor tyrosine kinases, effectively suppressing processes such as metastasis, angiogenesis, and oncogenesis, making it a versatile therapeutic
Enzymes: Antithrombin-IIINintedanib Action Pathway
smpdb.ca/view/SMP0126909Drug actionIt's indicated for idiopathic pulmonary fibrosis (IPF), systemic sclerosis-associated interstitial lung disease, and chronic fibrosing interstitial lung diseases with a progressive phenotype, where it
Enzymes: Antithrombin-IIIBrolucizumab Action Pathway
smpdb.ca/view/SMP0126913Drug actionIt functions as a vascular endothelial growth factor (VEGF) inhibitor, specifically targeting major VEGF-A isoforms (VEGF110, VEGF121, and VEGF165). … Patients should be informed about potential risks, including endophthalmitis, retinal detachment, and arterial thromboembolic events, associated with this medication.
Enzymes: Antithrombin-IIIParnaparin Action Pathway
smpdb.ca/view/SMP0126175Drug actionParnaparin is a low-weight molecular heparin (LWMH), an anticoagulant that acts on antithrombin III in order to inhibit coagulation. … Inhibition of antithrombin III leads to no conversion of prothrombin to thrombin in addition to halting the conversion of fibrinogen to fibrin due to little concentrations of thrombin.
Drugs: CalciumEnzymes: Antithrombin-IIIEnoxaparin Prothrombin Anticoagulation Action Pathway
smpdb.ca/view/SMP0126448Drug actionIt has an immediate onset of action, it binds to antithrombin III, inhibiting factor Xa ceasing the conversion of prothrombin to thrombin. … Enoxaparin can interact with some herbs and supplements, avoid those with anticoagulant and antiplatelet activity such as garlic, ginger, bilberry, danshen, piracetam and ginkgo biloba.
Enzymes: Antithrombin-III