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Displaying results 111 - 120 of 9754 in total
  1. Drug

    Eurotium amstelodami

    go.drugbank.com/drugs/DB15526
    Approved

    Eurotium amstelodami allergenic extract is used in allergenic testing.

    Synonyms: Molds, rusts and smuts, aspergillus amsterdami
  2. Drug

    Atacicept

    go.drugbank.com/drugs/DB06399
    ApprovedInvestigational

    factor (BAFF) and A Proliferation Inducing Ligand (APRIL). … [L63797] Reducing BAFF- and APRIL-mediated signaling lowers production of galactose-deficient IgA1, an aberrant antibody whose deposition in the kidney drives IgA nephropathy.

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein (Fc5)
  3. Drug

    Zenocutuzumab

    go.drugbank.com/drugs/DB15559
    ApprovedInvestigational

    Zenocutuzumab is a low-fucose humanized full-length immunoglobulin G1 (IgG1) bispecific HER2- and HER3-directed bispecific antibody. … [L56179] This approval was expedited following receipt of an FDA Commissioner’s National Priority Voucher.

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: Mcla-128 (igg1 bispecific antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and her3 receptors.), Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized clone mcla-128 .gamma.1-chain), disulfide with humanized clone mcla-128 light chain, dimer
  4. Drug

    N-alkyl ethylbenzyl dimethyl ammonium (C12-C14)

    go.drugbank.com/drugs/DB11202
    Approved

    and exposure, although the formal mechanism of action of quaternary ammonium compounds like n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is difficult to elucidate. … Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive and gram-negative antibacterial activities and relatively little chance for systemic absorption

    Salts: N-alkyl ethylbenzyl dimethyl ammonium chloride (C12-C14)Mixtures: Prevent X Hand Sanitizer and Antiseptic Skin Protectant, Antimicrobial Hand Cleaner
  5. Drug

    Ipratropium

    go.drugbank.com/drugs/DB00332
    ApprovedInvestigational

    [A176957] Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved in 1986, while the combination product of ipratropium and [albuterol … Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent.

    Salts: Ipratropium chlorideMixtures: Ipratropium Bromide and Albuterol Sulfate, Ipratropium Bromide and Albuterol Sulfate
  6. Drug

    Chromium Cr-51

    go.drugbank.com/drugs/DB11140
    ApprovedInvestigational

    blood cell survival time and evaluate blood loss. … Chromium Cr-51 is an isotope of chromium that has been used as a radioactive label for decades.

    Salts: Chromium Cr-51 chloride
  7. Drug

    Talquetamab

    go.drugbank.com/drugs/DB16678
    ApprovedInvestigational

    It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. … [L47765] Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and CD3 on T cells.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: ANTIBODY; BISPECIFIC GAMMA4 HEAVY CHAIN HUMANIZED AN, IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL
  8. Drug

    Vaccinia virus, modified encoding ebola virus glycoprotein and nucleoprotein

    go.drugbank.com/drugs/DB33819
    Experimental

    Synonyms: Vaccinia virus, modified encoding ebola virus glycoprotein and nucleoprotein
  9. Drug

    Apadamtase alfa

    go.drugbank.com/drugs/DB15164
    ApprovedInvestigational

    Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. … for cleaving large von Willebrand factor multimers and preventing the formation of microthrombi - this deficiency in ADAMTS13 is responsible for the microangiopathic complications associated with cTTP

    Categories: Enzymes and Coenzymes, Blood and Blood Forming OrgansSynonyms: Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs
  10. Drug

    Benzoxonium

    go.drugbank.com/drugs/DB13565
    Experimental

    Salts: Benzoxonium chlorideCategories: benzoxonium chloride, benzoxonium chloride