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Displaying results 1191 - 1200 of 10000 in total
  1. Drug

    Levonorgestrel

    go.drugbank.com/drugs/DB00367
    ApprovedInvestigational

    [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. … Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone therapy.

    Synonyms: 13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one, 17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-oneMixtures: CYCLO PROGYNOVA N 2MG/0.15, CYCLO PROGYNOVA N 2MG/0.15
  2. Drug

    Osimertinib

    go.drugbank.com/drugs/DB09330
    ApprovedInvestigational

    testing and which has progressed following therapy with a first-generation EGFR tyrosine kinase inhibitor. … Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs due to the presence of specific activating EGFR mutations within the tumour cells.

    Synonyms: N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamideCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  3. Drug

    Benoxaprofen

    go.drugbank.com/drugs/DB04812
    ApprovedWithdrawn

    The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.

    Synonyms: (1)-2-(4-Chlorophenyl)benzoxazole-5-propionic acid, 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid
  4. Drug

    Liothyronine

    go.drugbank.com/drugs/DB00279
    ApprovedInvestigationalVet approved

    Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. … Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine.

    Synonyms: 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosineMixtures: BITIRON 50 MCG/12.5 MCG TABLET, 100 ADET, NP Thyroid 60
  5. Drug

    Celgosivir

    go.drugbank.com/drugs/DB06580
    Investigational

    Synonyms: 6-O-ButanoylcastanospermineCategories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Mivavotinib

    go.drugbank.com/drugs/DB16849
    Investigational

    Synonyms: 6-{[(1r,2s)-2-Aminocyclohexyl]amino}-7-Fluoro-4-(1-Methyl-1h-Pyrazol-4-Yl)-1,2-Dihydro-3h-Pyrrolo[3,4-C]pyridin-3-One
  7. Drug

    6-amino-1-methyl-7H-purin-1-ium

    go.drugbank.com/drugs/DB03164
    Experimental

    Synonyms: 6-amino-1-methyl-7H-purin-1-ium, 6-amino-1-methylpurine
  8. Drug

    Shogaol

    go.drugbank.com/drugs/DB20280
    Experimental

    Shogaol is a small molecule drug. Shogaol has a monoisotopic molecular weight of 276.17 Da.

    Synonyms: (6)-shogaol
  9. Drug

    Aztreonam

    go.drugbank.com/drugs/DB00355
    ApprovedInvestigational

    It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms. … A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum.

    Synonyms: (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid, 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene]amino}oxy)-2-methylpropanoic acidCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  10. Drug

    PLX51107

    go.drugbank.com/drugs/DB17543
    Investigational

    PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family. … [A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Benzoic acid, 4-(6-(3,5-dimethyl-4-isoxazolyl)-1-((1s)-1-(2-pyridinyl)ethyl)-1h-pyrrolo(3,2-b)pyridin-3-yl)-