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Benzoin resin
go.drugbank.com/drugs/DB11222ApprovedBenzoin resin is a balsamic resin obtained from the bark of several species of trees in the genus Styrax. There are two common kinds of benzoin, benzoin Siam and benzoin Sumatra, that are obtained from different species of the Styrax tre...
Mixtures: Blistex Kank-AEtranacogene dezaparvovec
go.drugbank.com/drugs/DB16791ApprovedInvestigational[L44161] Men are most likely to experience symptomatic illness due to the X-linked provenance of the disorder. … Hemophilia B - also called factor IX deficiency or Christmas disease - is an X-linked genetic disorder resulting in an absence or deficiency of clotting factor IX.
Buclizine
go.drugbank.com/drugs/DB00354ApprovedBuclizine is an antihistamine medication with both antiemetic and anticholinergic effects [L6220], belonging to the _piperazine derivative_ family of drugs. … [L6217] Following this, it was touted to be effective as an appetite stimulant in children when administered in the syrup form, however, this indication has not been validated.
Synonyms: 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazineCarbenicillin
go.drugbank.com/drugs/DB00578ApprovedBroad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Lumasiran
go.drugbank.com/drugs/DB15935ApprovedInvestigational[L23554] This condition, caused by a deficiency in the enzyme alanine-glyoxylate aminotransferase, leads to an accumulation of oxalate, causing calcium crystal formation.
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Enzyme InhibitorsLacidipine
go.drugbank.com/drugs/DB09236ApprovedDue to its long duration of action, lacidipine does not lead to reflex tachycardia [A31536]. … Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPolymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B was discovered in the 1940s . They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes . Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxi...
Mixtures: OTEK-P EAR DROPS, PS-2261 Triple Antibiotic, 0.5gProducts: POLİX 500000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ (POLİMİSİN), 10 FLAKON, POLİX 500000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ (POLİMİSİN), 1 FLAKONFinerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigationalmineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and hospitalization due … [A236544] Spironolactone has low selectivity and affinity for the receptor; it dissociates quickly and can also have effects at the androgen, progesterone, and glucocorticoid receptors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesTick-borne encephalitis vaccine (whole virus, inactivated)
go.drugbank.com/drugs/DB16611ApprovedInvestigational[A237520] Due to a paucity of effective safe and effective acute therapeutic agents, vaccination remains the most important defence against TBE in endemic areas. … [A237505, A237520] While some patients recover fully following neurological TBE, neurological sequelae can last for years and rare chronic forms of the disease have also been noted.
Miltefosine
go.drugbank.com/drugs/DB09031ApprovedInvestigationalIt can be administered topically or orally and is only indicated in patients aged 12 years or older. … Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent.
Categories: P-glycoprotein substrates