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Cardiolipin Biosynthesis CL(8:0/25:0/25:0/25:0)
smpdb.ca/view/SMP0288261MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Tezepelumab
go.drugbank.com/drugs/DB15090ApprovedInvestigationalBlocking the interaction of TSLP with the receptors TSLPR and IL-7Rα improves asthma-associated biomarkers including eosinophil counts and IgE, FeNO, IL-5, and IL-13 levels. … [A243764, A243769] Thymic stromal lymphopoietin (TSLP), an innate pleiotropic IL-2-family cytokine, has emerged as a key upstream regulator of chronic inflammation across asthma endotypes.
Synonyms: AMG 157, AMG-157Products: Tezspire 210 mg/1,91 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet), TEZSPIRE®Antilymphocyte immunoglobulin (horse)
go.drugbank.com/drugs/DB09312ApprovedInvestigationalInduction of T cell apoptosis and resulting T-cell lymphopenia found in vivo is credited for its therapeutic effect in these conditions. … It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen.
Synonyms: e-ATG, h-ATGCategories: Immunoglobulin G, Increased T Lymphocyte DestructionAsparaginase Escherichia coli
go.drugbank.com/drugs/DB00023ApprovedInvestigationalAsparaginase derived from _Escherichia coli_ (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia … Therapeutic L-asparaginase from _E. coli_ works by depleting the levels of non-essential amino acid, asparagine, in lymphoblastic leukemic cells thus promoting apoptotic cell death [A31999].
Synonyms: L-Asnase, L-asparaginaseProducts: KIDROLASE 10000 UI, LEUNASE ENJEKTABL 10.000 IU FLAKON, 1 ADETLevocabastine
go.drugbank.com/drugs/DB01106ApprovedLevocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.
Categories: Heterocyclic Compounds, 1-RingProducts: Levocamed 0,5 mg/ml Augentropfensuspension, Levocamed 0,5 mg/ml Nasenspray, SuspensionCardiolipin Biosynthesis CL(10:0/25:0/25:0/25:0)
smpdb.ca/view/SMP0179155MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(16:0/25:0/25:0/25:0)
smpdb.ca/view/SMP0208314MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Remifentanil
go.drugbank.com/drugs/DB00899ApprovedInvestigationalRemifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia. … Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic.
Categories: Heterocyclic Compounds, 1-RingProducts: ULTIVA INYECTABLE 5 MG, REKSİVA 5 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 5 ADETTrabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalIt is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma. … On October 23, 2015, the FDA approved trabectedin, (as Yondelis), for the treatment of specific soft tissue sarcomas.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexProducts: Trabectedin SUN 1 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Trabectedin SUN 0,25 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungTrihexyphenidyl
go.drugbank.com/drugs/DB00376ApprovedInvestigational[L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity. … [A229103] Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment due to significant adverse effects.
Categories: Heterocyclic Compounds, 1-RingProducts: ACA (5 mg.), BENZHEXOL TABLETS 5 MG