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Imlunestrant
go.drugbank.com/drugs/DB19043ApprovedInvestigationalImlunestrant is a brain-penetrant selective estrogen receptor antagonist and degrader. The FDA approved imlunestrant on September 25, 2025 as a treatment for estrogen receptor (ER)-positive, HER2-negative, estrogen receptor 1 (ESR1)-muta...
Categories: Cytochrome P-450 CYP2B6 Inhibitors, Cytochrome P-450 SubstratesBenzgalantamine
go.drugbank.com/drugs/DB19353ApprovedInvestigationalBenzgalantamine is a prodrug of galantamine. Gastrointestinal adverse effects are the most frequently reported side effects in patients undergoing treatment with cholinesterase inhibitors, including galantamine, and are often a reason fo...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesHydrastine
go.drugbank.com/drugs/DB19354ExperimentalCategories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 CYP2C9 SubstratesSetileuton
go.drugbank.com/drugs/DB19550InvestigationalSetileuton is a small molecule drug. The usage of the INN stem '-leuton' in the name indicates that Setileuton is a 5-lipo-oxygenase inhibitor, anti-inflammatory. Setileuton is under investigation in clinical trial NCT00404313 (The Effec...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesMifentidine
go.drugbank.com/drugs/DB19721ExperimentalMifentidine is a small molecule drug. The usage of the INN stem '-tidine' in the name indicates that Mifentidine is a histamine- H2-receptor antagonist, cimetidine derivative. Mifentidine has a monoisotopic molecular weight of 228.14 Da.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsLefetamine
go.drugbank.com/drugs/DB19944ExperimentalLefetamine is a small molecule drug. Lefetamine has a monoisotopic molecular weight of 225.15 Da.
Categories: Cytochrome P-450 CYP1A2 Substrates, Cytochrome P-450 SubstratesTauromustine
go.drugbank.com/drugs/DB19978ExperimentalTauromustine is a small molecule drug. The usage of the INN stem '-mustine' in the name indicates that Tauromustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative. Tauromustine has a monoisotopic molecular weight...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesCloperidone
go.drugbank.com/drugs/DB20327ExperimentalCloperidone is a small molecule drug. Cloperidone has a monoisotopic molecular weight of 398.15 Da.
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 SubstratesMofarotene
go.drugbank.com/drugs/DB20333ExperimentalMofarotene is a small molecule drug. The usage of the INN stem '-arotene' in the name indicates that Mofarotene is a arotinoid derivative. Mofarotene has a monoisotopic molecular weight of 433.3 Da.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesNavamepent
go.drugbank.com/drugs/DB21096InvestigationalNavamepent is a small molecule drug. Navamepent is under investigation in clinical trial NCT02329743 (Efficacy and Safety of RX-10045 Ophthalmic Solution for Ocular Inflammation and Pain in Cataract Surgery). Navamepent has a monoisotopi...
Categories: P-glycoprotein inhibitors