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Displaying results 1211 - 1220 of 10000 in total
  1. Drug

    Centella asiatica

    go.drugbank.com/drugs/DB14256
    Approved

    Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: MADECASSOL CSynonyms: Luo De Da Whole, Ma Ti Cao Whole
  2. Target

    Homeobox protein engrailed-2

    go.drugbank.com/bio_entities/BE0004484
    TargetHumans

    Synonyms: Hu-En-2, Homeobox protein en-2
  3. Indication

    Venous Thrombosis caused by procedures associated with a high incidence of thromboembolic complications

    go.drugbank.com/conditions/DBCOND0106269
    Drugs: Dextran
    Synonyms: Venous Thrombosis caused by procedures associated with a high incidence of thromboembolic complications
  4. Drug

    Gemcitabine

    go.drugbank.com/drugs/DB00441
    ApprovedInvestigational

    Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. … [A233135] Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesSynonyms: 2'-Deoxy-2',2'-difluorocytidine, 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
  5. Drug

    Triprolidine

    go.drugbank.com/drugs/DB00427
    Approved

    First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.

    Mixtures: Ed-A-hist Pse, A-FERIN DECO ŞURUP, 100 MLCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Activated charcoal

    go.drugbank.com/drugs/DB09278
    ApprovedInvestigational

    It works by binding to the poison in the gastric contents in a reversible fashion thus may be adminstered together with a cathartic to reduce the small intestine transit time. … It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high affinity for various substances

    Mixtures: FINIGAX®, FINIGAX® CAPSULASCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Rabeprazole

    go.drugbank.com/drugs/DB01129
    ApprovedInvestigational

    Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. … Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.

    Categories: Cytochrome P-450 Substrates, 2-PyridinylmethylsulfinylbenzimidazolesProducts: Rabeprazol 1A Pharma 10 mg - magensaftresistente Tabletten, Rabeprazol 1A Pharma 20 mg - magensaftresistente Tabletten
  8. Drug

    Alfuzosin

    go.drugbank.com/drugs/DB00346
    Approved

    Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. … [A228483] Alfuzosin is an alpha-1 adrenergic blocker used in the symptomatic treatment of BPH that works by relaxing the muscles in the prostate and bladder neck.

    Categories: Drugs Used in Benign Prostatic Hypertrophy, Cytochrome P-450 SubstratesSynonyms: (±)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furamide, N-[3-[(4-amino-6,7-dimethoxy-quinazolin-2-yl)- methyl-amino]propyl] tetrahydrofuran- 2-carboxamide
  9. Drug

    Mannitol

    go.drugbank.com/drugs/DB00742
    ApprovedInvestigational

    Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. … Mannitol may also be used for the promotion of diuresis before irreversible renal failure becomes established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a

    Synonyms: D-Mannitol, D-(-)-MannitolInternational brands: Mannisol A
  10. Target

    Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

    go.drugbank.com/bio_entities/BE0004551
    TargetHumans

    Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly ...

    Polypeptides: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1