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Displaying results 1211 - 1220 of 7181 in total
  1. Drug

    Voxelotor

    go.drugbank.com/drugs/DB14975
    Approved

    [L10403] and is unique from other drugs used to treat sickle cell anemia, such as [hydroxyurea], [L-glutamine], and [crizanlizumab][A188135,A188138] due to its novel mechanism of action. … Sickle cell disease can lead to excruciating pain, stroke, infection, and various other complications arising from the blockage of blood vessels.

  2. Drug

    Stannous fluoride

    go.drugbank.com/drugs/DB11092
    ApprovedInvestigational

    Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective at stopping and reversing dental … Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity.

    Products: Complete Protection TP, Colgate Co Oh So Glowing
  3. Drug

    Gabapentin

    go.drugbank.com/drugs/DB00996
    ApprovedInvestigational

    It is structurally and functionally related to another GABA derivative, [pregabalin]. … [L8717] It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic pain.

    Mixtures: GAVINDO NProducts: Nu-gabapentin Capsules
  4. Indication

    Chronic Angle Closure Glaucoma

    go.drugbank.com/conditions/DBCOND0036703
    Drugs: Echothiophate
    Synonyms: Angle closure glaucoma due to peripheral anterior synechiae, Angle closure glaucoma due to peripheral anterior synechiae (disorder)
  5. Drug

    Arginine

    go.drugbank.com/drugs/DB00125
    ApprovedInvestigationalNutraceutical

    An essential amino acid that is physiologically active in the L-form.

    Mixtures: ABOUND PORTAKAL AROMALI TOZ 24 GR 30 POSET, AMINOSTERIL N-HEPA 8%
  6. Indication

    Herpes simplex encephalitis

    go.drugbank.com/conditions/DBCOND0013826
    Drugs: Acyclovir
    Synonyms: Encephalitis due to Herpesvirus
  7. Drug

    Sirolimus

    go.drugbank.com/drugs/DB00877
    ApprovedInvestigational

    Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria _Streptomyces hygroscopicus_, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island … [A242372] In November 2000, the drug was recognized by the European Agency as an alternative to calcineurin antagonists for maintenance therapy with corticosteroids.

  8. Drug

    Oxycodone

    go.drugbank.com/drugs/DB00497
    ApprovedIllicitInvestigational

    Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics

    Mixtures: Nu-oxycodone/acet, OXYCODON/NALOXON-NX 10/5Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  9. Drug

    Cyclosporine

    go.drugbank.com/drugs/DB00091
    ApprovedInvestigationalVet approved

    It is isolated from the fungus _Beauveria nivea_. … [A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]

    Products: DNACIPOL-N, SANDIMMUN LOESUNG Z EINNEH
  10. Drug

    Tryptophan

    go.drugbank.com/drugs/DB00150
    ApprovedInvestigationalNutraceuticalWithdrawn

    It can be a precursor to niacin, albeit inefficiently, in mammals.

    Mixtures: Vamin N, AMINOSTERIL N-HEPA 8%Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome