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Displaying results 1211 - 1220 of 10000 in total
  1. Drug

    PCO-371

    go.drugbank.com/drugs/DB14946
    Investigational

    PCO-371 is under investigation in clinical trial NCT02475616 (A Single Ascending Dose Study of PCO371 in Healthy Volunteers).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,4-IMIDAZOLIDINEDIONE, 1-(3,5-DIMETHYL-4-(2-((4-OXO-2-(4-(TRIFLUOROMETHOXY)PHENYL)-1,3,8-TRIAZASPIRO(4.5)DEC-1-EN-8-YL)SULFONYL)ETHYL)PHENYL)-5,5-DIMETHYL-, non-peptide small molecule orally available agonist of the parathyroid hormone receptor type I
  2. Drug

    3'-1-carboxy-1-phosphonooxy-ethoxy-uridine-diphosphate-N-acetylglucosamine

    go.drugbank.com/drugs/DB04174
    Experimental

    Synonyms: 3'-1-carboxy-1-phosphonooxy-ethoxy-uridine-diphosphate-N-acetylglucosamine
  3. Drug

    D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate

    go.drugbank.com/drugs/DB02393
    Experimental

    Synonyms: D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate
  4. Drug

    Tripotassium (1R)-4-biphenyl-4-yl-1-phosphonatobutane-1-sulfonate

    go.drugbank.com/drugs/DB07424
    Experimental

    Synonyms: Tripotassium (1R)-4-biphenyl-4-yl-1-phosphonatobutane-1-sulfonate
  5. Drug

    Vinflunine

    go.drugbank.com/drugs/DB11641
    ApprovedInvestigational

    Vinflunine is a third-generation member of the vinca alkaloid family with anti-tumour actions. It was first described in 1998 at the Pierre Fabre research center in France. … Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death via apoptosis [L1396].

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastine, 20',20'-difluoro-3',4'-dihydrovinorelbine
  6. Drug

    (2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine

    go.drugbank.com/drugs/DB06993
    Experimental

    Synonyms: (2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine
  7. Drug

    Triciribine phosphate

    go.drugbank.com/drugs/DB14636
    Investigational

    Synonyms: 3-AMINO-1,5-DIHYDRO-5-METHYL-1-.BETA.-D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLENE 5'-(DIHYDROGEN PHOSPHATE), Pentaazaacenaphthylene-5' phosphate ester
  8. Drug

    Naloxone

    go.drugbank.com/drugs/DB01183
    ApprovedInvestigationalVet approved

    [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors. … [L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use.

    Mixtures: Bupensan Duo 4 mg/1 mg-Sublingualtabletten, TARGIN (R) 10 MG / 5 MG TABLETAS DE LIBERACIÓN PROLONGADACategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  9. Drug

    Metronidazole benzoate

    go.drugbank.com/drugs/DB15759
    Investigational

    Mixtures: METRONIDAZOL BENZOILO/ NIFUROXAZIDA 250MG + 200MG/5 ML SUSPENSION, DIARSET NX- M SUSPENSIONCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Rifalazil

    go.drugbank.com/drugs/DB04934
    Investigational

    Rifalazil is a derivative of the antibiotic rifamycin. It is being investigated by ActivBiotics for the treatment of various bacterial infections.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin