This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Metronidazole benzoate
DrugBank Accession Number
DB15759
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 275.264
Monoisotopic: 275.090605911
Chemical Formula
C13H13N3O4
Synonyms
  • 2-(2-Methyl-5-nitroimidazol-1-yl)ethyl benzoate
  • Benzoyl metronidazole
  • Benzoylmetronidazole
  • Metronidazol benzoilo
  • Metronidazole benzoate

Pharmacology

Indication

Not Available

Reduce drug development failure rates
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Associated Conditions
Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug events
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Avoid life-threatening adverse drug events & improve clinical decision support.
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Improve decision support & research outcomes with our structured adverse effects data.
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
KRODEX F COMPUESTO SUSPENSIÓNMetronidazole benzoate (5 g) + Nifuroxazide (4 g)SuspensionOralCOASPHARMA S.A.S.2007-02-06Not applicableColombia flag
METRO F SUSPENSIONMetronidazole benzoate (5 g) + Nifuroxazide (4 g)SuspensionOralCOLOMPACK S.A.2018-09-25Not applicableColombia flag
METRONIF SUSPENSIONMetronidazole benzoate (5 g) + Nifuroxazide (4 g)SuspensionOralPROCAPS S.A.2006-11-10Not applicableColombia flag
METROSHERMetronidazole benzoate (5 g) + Nifuroxazide (4 g)SuspensionOralCOLOMPACK S.A.2008-10-032018-12-26Colombia flag
METROXAZIDE® SUSPENSIÒNMetronidazole benzoate (5 g) + Nifuroxazide (4 g)SuspensionOralGONHER FARMACEUTICA LTDA PLANTA DE PRODUCCIÓN II2007-06-152017-06-28Colombia flag
STOMAVIDNH SUSPENSIONMetronidazole benzoate (5 g) + Nifuroxazide (4 g)SuspensionOralCOLOMPACK S.A.2018-06-26Not applicableColombia flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
A355C835XC
CAS number
13182-89-3
InChI Key
CUUCCLJJOWSASK-UHFFFAOYSA-N
InChI
InChI=1S/C13H13N3O4/c1-10-14-9-12(16(18)19)15(10)7-8-20-13(17)11-5-3-2-4-6-11/h2-6,9H,7-8H2,1H3
IUPAC Name
2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl benzoate
SMILES
CC1=NC=C(N1CCOC(=O)C1=CC=CC=C1)[N+]([O-])=O

References

General References
Not Available
ChemSpider
75079
RxNav
103866
ChEBI
50688
ChEMBL
CHEMBL1466172
ZINC
ZINC000000163922
Wikipedia
Metronidazole

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedTreatmentChronic Periodontitis (Disorder)1
1CompletedNot AvailableHealthy Subjects (HS)1
1CompletedBasic ScienceHealthy Subjects (HS)1
1CompletedTreatmentBacterial Infections1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SuspensionOral5 g
SuspensionOral2.5 g
SuspensionOral
SuspensionOral5 g
SuspensionOral
PowderNot applicable1 g/1g
SuspensionOral125 MG/5ML
InjectionIntravenous
SuspensionOral8 g
SuspensionOral200 ml/5ml
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.236 mg/mLALOGPS
logP1.71ALOGPS
logP2.04Chemaxon
logS-3.1ALOGPS
pKa (Strongest Basic)3.27Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area87.26 Å2Chemaxon
Rotatable Bond Count6Chemaxon
Refractivity70.04 m3·mol-1Chemaxon
Polarizability27.2 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at August 17, 2020 21:00 / Updated at February 21, 2021 18:55