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Displaying results 1221 - 1230 of 2440 in total
  1. Drug

    Repotrectinib

    go.drugbank.com/drugs/DB16826
    ApprovedInvestigational

    Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  2. Drug

    Rhodamine B

    go.drugbank.com/drugs/DB16853
    Experimental

    Categories: P-glycoprotein substrates
  3. Drug

    Tanshinone I

    go.drugbank.com/drugs/DB16886
    Experimental

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
  4. Drug

    BPR-0L075

    go.drugbank.com/drugs/DB17155
    Investigational

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  5. Drug

    EP-0042

    go.drugbank.com/drugs/DB18120
    Investigational

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  6. Drug

    Ferroheme

    go.drugbank.com/drugs/DB18267
    Investigational

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
  7. Drug

    Fenvalerate

    go.drugbank.com/drugs/DB18391
    Experimental

    Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 CYP3A Inhibitors
  8. Drug

    Befotertinib

    go.drugbank.com/drugs/DB18844
    Investigational

    Befotertinib is under investigation in clinical trial NCT05007938 (Befotertinib and Icotinib in Treatment-naive Patients With Advanced Egfr-mutant Lung Cancer).

    Categories: P-glycoprotein inhibitors
  9. Drug

    Avenciguat

    go.drugbank.com/drugs/DB18882
    Investigational

    Avenciguat is under investigation in clinical trial NCT05282121 (A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (N...

    Categories: P-glycoprotein substrates
  10. Drug

    Epaminurad

    go.drugbank.com/drugs/DB18973
    Investigational

    Epaminurad is under investigation in clinical trial NCT05815901 (A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout Patients).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates