Avenciguat
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Avenciguat
- DrugBank Accession Number
- DB18882
- Background
Avenciguat is under investigation in clinical trial NCT05282121 (A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 582.701
Monoisotopic: 582.28422034 - Chemical Formula
- C34H38N4O5
- Synonyms
- Avenciguat
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- ZA7KTB4PSP
- CAS number
- 1579514-06-9
- InChI Key
- KWNFFNFBUMFTHK-UHFFFAOYSA-N
- InChI
- InChI=1S/C34H38N4O5/c1-4-42-33-29(34(39)40)19-35-38(33)31-10-6-9-30(36-31)28-8-5-7-22(2)32(28)43-21-25-12-11-24-20-37(16-13-27(24)23(25)3)26-14-17-41-18-15-26/h5-12,19,26H,4,13-18,20-21H2,1-3H3,(H,39,40)
- IUPAC Name
- SMILES
- CCOC1=C(C=NN1C1=CC=CC(=N1)C1=CC=CC(C)=C1OCC1=CC=C2CN(CCC2=C1C)C1CCOCC1)C(O)=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 128921322
- Wikipedia
- Avenciguat
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data2 Completed Treatment Chronic Kidney Disease (CKD) 1 somestatus stop reason just information to hide 2 Recruiting Treatment Scleroderma, Systemic 1 somestatus stop reason just information to hide 2 Terminated Treatment Cirrhosis of the Liver / Portal Hypertension 1 somestatus stop reason just information to hide 2 Terminated Treatment Liver Disease / Portal Hypertension 1 somestatus stop reason just information to hide 2 Terminated Treatment Portal Hypertension 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at June 26, 2024 22:10 / Updated at June 27, 2024 01:29