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Phosphatidyl serine
go.drugbank.com/drugs/DB00144ApprovedNutraceuticalPhosphatidyl serine (PS) is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and rice, and is essential for the normal functioning of neuronal cell membranes and activates Protein … PS has been investigated in a small number of double-blind placebo trials and has been shown to increase memory performance in the elderly.
Mixtures: Enlalpha-Linolenic acid
go.drugbank.com/drugs/DB00132ApprovedInvestigationalNutraceuticalWithdrawnAlpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Mixtures: Bio-efa Borage Gla 90 Cap, PRIM E CAPSULESynonyms: ALANeon
go.drugbank.com/drugs/DB11589ApprovedNeon may be used in the clinical setting as a diagnostic tracer gas in a gas analyzer for a lung diffusion test. … It is the fifth most abundant chemical element in the universe by mass but a rare element on Earth.
Mixtures: Co-NE-O2-N2 Mixture, Lung Diffusion Test Mix No Ne CoSynonyms: NeNonoxynol-9
go.drugbank.com/drugs/DB06804ApprovedWithdrawnNonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. … N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants.
Categories: Compounds used in a research, industrial, or household setting, Hormonal Contraceptives for Systemic UseMepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalEosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm<sup>3</sup> or more) is associated with a spectrum … Mepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma and marketed under the brand name Nucala by GlaxoSmithKline.
Categories: Drugs for Obstructive Airway DiseasesProducts: NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML, Nucala 100mg/ml Solution for Injection in pre-filled pen (Autoinjector)Durvalumab
go.drugbank.com/drugs/DB11714ApprovedInvestigational[L12621] In September 2018, durvalumab was approved by the EMA for the treatment of adult patients with locally advanced, unresectable non-small cell lung cancer (NSCLC), only if PD-L1 is expressed in … Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: IMFINZI CONCENTRATE FOR SOLUTION FOR INFUSION 50 MG/ML, IMFINZI CONCENTRATE FOR SOLUTION FOR INTRAVENOUS INFUSION 50 MG/MLZanidatamab
go.drugbank.com/drugs/DB15471ApprovedInvestigational[A264718] In November 2024, the FDA granted an accelerated approval for zanidatamab for use in previously treated unresectable or metastatic HER2-positive biliary tract cancers.[L51908,L51903] … Zanidatamab is a bispecific antibody that binds two non-overlapping sites of HER2 (ERBB2).
Nicoboxil
go.drugbank.com/drugs/DB12911ApprovedWithdrawnSuch combination topical analgesics are only available for purchase and use (for humans) in some parts of Europe and Asia, like Germany and Australia [F11, F16]. … Nicoboxil has been investigated for the treatment of Acute Low Back Pain, where it is typically considered an effective and safe therapeutic option.
Mixtures: Actinac PwrRelatlimab
go.drugbank.com/drugs/DB14851ApprovedInvestigational[L41300] Opdualag was subsequently approved in the European Union in July 2022[L49996] and in Canada in September 2023.[L50001] … [L41265,L41300] It was the first anti-LAG-3 antibody to demonstrate benefit in a Phase 3 study, as well as the first to receive FDA approval.
Pegulicianine
go.drugbank.com/drugs/DB18731ApprovedInvestigationalPegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer. … [L50537] Pegulicianine (under the brand name Lumisight) was approved for use by the FDA in April 2024.[L50537,L50547] It received Fast Track and priority review for this indication.[L50547]
Categories: Compounds used in a research, industrial, or household setting