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Displaying results 1231 - 1240 of 5758 in total
  1. Drug

    Encorafenib

    go.drugbank.com/drugs/DB11718
    ApprovedInvestigational

    Encorafenib, also known as BRAFTOVI, is a kinase inhibitor. Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in various genetic mutations. This protein plays a role in regulating the MAP...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  2. Drug

    PF-03758309

    go.drugbank.com/drugs/DB11775
    Investigational

    PF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors.

    Salts: Pf 03758309 Hydrochloride
  3. Drug

    PF-477736

    go.drugbank.com/drugs/DB12611
    Investigational

    PF-00477736 has been used in trials studying the treatment of Neoplasms.

  4. Drug

    PF-04217903

    go.drugbank.com/drugs/DB12848
    Investigational

    PF-04217903 has been used in trials studying the treatment of Neoplasms.

  5. Drug

    PI-103

    go.drugbank.com/drugs/DB17046
    Experimental

    PI-103 is an inhibitor of p110α of class I PI3K.[A253092]

  6. Drug

    Dienogest

    go.drugbank.com/drugs/DB09123
    ApprovedInvestigational

    Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive i...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    PF-06273340

    go.drugbank.com/drugs/DB12269
    Investigational

    Pf 06273340 is under investigation in clinical trial NCT01934738 (A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects

  8. Drug

    Upleganan

    go.drugbank.com/drugs/DB21618
    Investigational

    Upleganan has a monoisotopic molecular weight of 1143.6 Da. … Upleganan is under investigation in clinical trial NCT04865393 (Phase 1 Study of PK and Safety of SPR206 in Subjects With Various Degrees Of Renal Function).

  9. Drug

    CLX-0921

    go.drugbank.com/drugs/DB05854
    Experimental

    This substance targets the protein peroxisome proliferator-activated receptor gamma.

  10. Drug

    Tibolone

    go.drugbank.com/drugs/DB09070
    ApprovedInvestigational

    Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic and progestogenic properties.