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Displaying results 1251 - 1260 of 10000 in total
  1. Drug

    6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE

    go.drugbank.com/drugs/DB07202
    Experimental

    Synonyms: 6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE
  2. Drug

    Phenoxypropazine

    go.drugbank.com/drugs/DB09251
    ApprovedWithdrawn

    Phenoxypropazine is a non-selective and irreversible monoamine oxidase enzyme inhibitor (MAOI), belonging to the _hydrazine_ chemical class.

    Synonyms: (1-METHYL-2-PHENOXYETHYL)HYDRAZINE, HYDRAZINE, (1-METHYL-2-PHENOXYETHYL)-
  3. Drug

    Acetylsalicylic acid

    go.drugbank.com/drugs/DB00945
    ApprovedInvestigationalVet approved

    Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. … Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].

    Synonyms: 2-Acetoxybenzoic acid, 2-Acetoxybenzenecarboxylic acidInternational brands: Nu-seals
  4. Drug

    Lacosamide

    go.drugbank.com/drugs/DB06218
    ApprovedInvestigational

    Lacosamide exhibits a stereoselective mode of interaction with sodium channels. … As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents.

    Synonyms: (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDE, (R)-2-acetamido-N-benzyl-3- methoxypropionamideMixtures: ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADET, ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADET
  5. Drug

    Bromhexine

    go.drugbank.com/drugs/DB09019
    ApprovedInvestigational

    Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. … [A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.

    Mixtures: BRONCODEX JARABE (GUAIFENESIN 2 G + BROMHEXINA HCI 0.08 G), ROBITUSSIN MESynonyms: N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine, 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine
  6. Drug

    VS-5584

    go.drugbank.com/drugs/DB12986
    Investigational

    VS-5584 has been used in trials studying the treatment of Lymphoma, Metastatic Cancer, and Non Hematologic Cancers.

    Synonyms: 2-pyrimidinamine, 5-(8-methyl-9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl)-, 5-[8-methyl-9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6yl]-2-pyrimidinamineCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-Ring
  7. Drug

    PHI-101

    go.drugbank.com/drugs/DB17237
    Investigational

    Synonyms: N-(2-(n-((3s)(3-piperidyl))carbamoyl)-5-(2-(3-fluorophenyl)ethynyl)(3-thienyl))aminamide, 2-thiophenecarboxamide, 3-((aminocarbonyl)amino)-5-(2-(3-fluorophenyl)ethynyl)-n-(3s)-3-piperidinyl-Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Lenalidomide

    go.drugbank.com/drugs/DB00480
    ApprovedInvestigational

    [A228553] It is a 4-amino-glutamyl analogue of [thalidomide] [A228543] and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. … [L16028] Due to severe teratogenicity, pregnancy must be excluded before the start of treatment and patients must enroll in the lenalidomide Risk Evaluation and Mitigation Strategy (REMS) program to ensure

    Synonyms: 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dioneCategories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates
  9. Drug

    Profenamine

    go.drugbank.com/drugs/DB00392
    Approved

    Profenamine (also known as ethopropazine) is a medication derived from phenothiazine. It is primarily used as an antidyskinetic to treat Parkinsonism.

    Categories: Heterocyclic Compounds, 3-RingSynonyms: 10-[2-(diethylamino)-2-methylethyl]phenothiazine, N,N-diethyl-1-(10H-phenothiazin-10-yl)-2-propanamine
  10. Drug

    Rofecoxib

    go.drugbank.com/drugs/DB00533
    ApprovedWithdrawn

    The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2. … Rofecoxib has a half-life of 17 hours and its mean oral bioavailability at therapeutically recommended doses of 125, 25, and 50 mg is approximately 93%.

    Synonyms: 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanoneCategories: COX-2 Inhibitors, Selective Cyclooxygenase 2 Inhibitors (NSAIDs)