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Rifabutin
go.drugbank.com/drugs/DB00615ApprovedInvestigationalA broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Synonyms: 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV, 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin SProducts: MYCOBUTIN 150 MG KAPSUL, 30 ADET, Mycobutin 150 mg - KapselnXylitol
go.drugbank.com/drugs/DB11195ApprovedInvestigationalThe recommended dose of xylitol for dental caries prevention is 6–10 g/day, and most adults can tolerate 40 g/day without adverse events [A22081]. … Xylitol is a non-fermentable sugar alcohol by most plaque bacteria, indicating that it cannot be fermented into cariogenic acid end-products [A32423].
Products: Xylifresh 100 (peppermint) - Gum 827 mg, Noble G PlusIsavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalIt is approved by the FDA and EMA for the treatment of invasive aspergillosis and mucormycosis. It works by inhibiting fungal cell membrane synthesis.
Categories: Heterocyclic Compounds, 1-RingProducts: CRESEMBA (100 MG HARD CAPSULES), CRESEMBA (POWDER FOR SOLUTION FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200 MG/VIAL)Nilotinib
go.drugbank.com/drugs/DB04868ApprovedInvestigationalNilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered si...
Categories: Heterocyclic Compounds, 1-RingProducts: TASIGNA® 150 MG CAPSULAS, TASIGNA 150 MG KAPSUL, 28 ADETAcebutolol
go.drugbank.com/drugs/DB01193ApprovedInvestigationalA cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Synonyms: N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamideCategories: Adrenergic beta-1 Receptor AntagonistsMigalastat
go.drugbank.com/drugs/DB05018ApprovedInvestigationalFabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). … [L47036,L47057,L4274,L4278] In these patients, migalastat works by stabilizing the body’s dysfunctional alpha-Gal A enzyme so that it can clear the accumulation of glycosphingolipid disease substrate.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-Deoxygalactostatin, 1-DeoxygalactonojirimycinAAG-1
go.drugbank.com/drugs/DB17199ExperimentalSynonyms: Furo(2,3-d)pyrimidin-4-amine, n-(4-methoxyphenyl)-n,2,6-trimethyl-, N-(4-methoxyphenyl)-n,2,6-trimethylfuro(2,3-d) pyrimidin-4-amineRacementhol
go.drugbank.com/drugs/DB14123ApprovedInvestigationalSynonyms: (1R,2S,5R)-Menthol, (±)-(1R*,3R*,4S*)-MENTHOLMixtures: Muscle and Joint pain relief GR Isolate 150 mg, Biofreeze Day and OvernightBinimetinib
go.drugbank.com/drugs/DB11967ApprovedInvestigationalEncorafenib] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients with unresectable or metastatic melanoma with the BRAF V600E or V600K mutations, as detected by … Binimetinib, also known as _Mektovi_, is a potent and selective oral mitogen-activated protein kinase 1/2 (MEK 1/2) inhibitor which is combined with [Encorafenib].
Categories: MAP Kinase Kinase 1, antagonists & inhibitorsProducts: MEKTOVI® 15 MG TABLETAS RECUBIERTAS, Mektovı 15 mg Film Kaplı Tablet, 84 ADETSimeprevir
go.drugbank.com/drugs/DB06290ApprovedWithdrawnThis class of antiviral drugs were the first direct acting antivirals approved but are associated with lower cure rates than newer drugs. … Like all NS3/4A inhibitors, simeprevir is a serine protease inhibitor in similarity to [DB08873] and [DB05521] but is classified as a second generation protease inhibitor.
Products: OLYSIO 150 MG KAPSUL ,KAPSUL, 28 ADET