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Displaying results 1261 - 1270 of 10000 in total
  1. Drug

    AMG-119

    go.drugbank.com/drugs/DB17363
    Investigational

    AMG-119 are CAR-T cells targeting delta-like ligand 3 (DLL3).[A254811]

  2. Drug

    Etrasimod

    go.drugbank.com/drugs/DB14766
    ApprovedInvestigational

    efficacy of a 2-mg daily dose regimen of etrasimod, with a 32% and 26% remission rate observed in UC 52 and UC 12 trials respectively. … [A261826] In fact, it has been observed that antigen-activated T cells within peripheral lymphoid organs can transiently downregulate S1P receptor levels to facilitate immune cells trafficking into the

  3. Drug

    Ripretinib

    go.drugbank.com/drugs/DB14840
    ApprovedInvestigational

    [L13769] It is the first drug approved as a fourth-line therapy in the specific setting of prior treatment with a minimum of 3 other kinase inhibitors.[L13778] … Ripretinib, also known as Qinlock, is manufactured by Deciphera Pharmaceuticals and was initially approved by the FDA on May 15, 2020.

  4. Drug

    Tegafur-uracil

    go.drugbank.com/drugs/DB09327
    Approved

    It was developed as an anti-cancer therapy by Taiho Pharmaceutical Co Ltd.[A32073] It is approved in different countries but it is not yet approved by the FDA, Health Canada or EMA. … Tegafur-uracil is an anti-tumor compound containing tegafur (1-(2-tetrahydrofuryl)-5-fluorouracil) and uracil in a molar ratio of 1:4.

  5. Drug

    Irinotecan

    go.drugbank.com/drugs/DB00762
    ApprovedInvestigational

    It is a water-soluble analogue of [camptothecin], which is extracted from the Chinese tree _Camptotheca acuminate_. … [A263381] As an anticancer drug, irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ovarian cancer.

    Products: IRINOTEL 40 MG/ 2 ML, CAMPTOLEM 100 MG/ 5 ML
  6. Drug

    Poliovirus type 2 antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10796
    ApprovedInvestigational

    The vaccine contains purified and inactivated poliovirus type 2 that were grown from a continuous line of monkey kidney cells. … Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis

    Mixtures: Dt Polio Adsorbed - Sus Im, VeroPol Injektionslösung in einer Fertigspritze
  7. Drug

    Magnesium sulfate

    go.drugbank.com/drugs/DB00653
    ApprovedInvestigationalVet approved

    It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. … A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia.

    Mixtures: Calcium Lactate Et Magnesium Sulfate, ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKISynonyms: Mg SO4, Mg sulfate
  8. Drug

    Chromium

    go.drugbank.com/drugs/DB11136
    ApprovedInvestigational

    It is used in various chemical, industrial and manufacturing applications such as wood preservation and metallurgy. … Trivalent chromium (Cr(III)) ion is considered to be an essential dietary trace element as it is involved in metabolism of blood glucose, regulation of insulin resistance and metabolism of lipids.

    Mixtures: Calcium With Mg Zn Mn Cu CR Si and Vit. C & D, Advanced B & T Formula
  9. Drug

    Atosiban

    go.drugbank.com/drugs/DB09059
    ApprovedInvestigational

    It was first reported in the literature in 1985. Atosiban is licensed in proprietary and generic forms for the delay of imminent pre-term birth in pregnant adult women. … Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form.

    Products: Atosiban Accord 6,75 mg/0,9 ml Injektionslösung in einer Fertigspritze, TRACTOCILE (7.5 MG/ML SOLUTION FOR INJECTION)
  10. Drug

    Rifamycin

    go.drugbank.com/drugs/DB11753
    ApprovedInvestigationalWithdrawn

    [L4800] This drug was also sent for review to the EMA in 2015 by Dr. Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801] … Product which allowed it to have a status a priority review.

    Mixtures: RIFOCIN 125 MG+5 MG/1,5 ML IM ENJEKSİYON İÇİN SOLÜSYON İÇEREN AMPUL, 100 ADET, RIF 125 MG 1 AMPULProducts: RIFAL IM 125 MG AMPUL, 1 ADET, RIFAL IM 250 MG AMPUL, 1 ADET