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Idursulfase
go.drugbank.com/drugs/DB01271ApprovedInvestigationalIdursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. … Idursulfase is a 525-amino acid glycoprotein with a molecular weight of approximately 76 kilodaltons.
Synonyms: Iduronate 2-sulfatase, Alpha-L-iduronate sulfate sulfataseProducts: ELAPRASE 2 MG/ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, Elaprase (TM) Solution for Intravenous Infusion 2mg/ mlPegcetacoplan
go.drugbank.com/drugs/DB16694ApprovedInvestigational[A235000] Patients given eculizumab experienced less hemolysis caused by the membrane attack complex, but were still somewhat susceptible to hemolysis caused by C3b opsonization. … Pegcetacoplan is a complement inhibitor indicated in the treatment of paroxysmal nocturnal hemoglobinuria (PNH).
Products: EMPAVELI® 54 MG/ML SOLUCIÓN INYECTABLEAjmaline
go.drugbank.com/drugs/DB01426ApprovedWithdrawnIt is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. … Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very useful drug for acute intravenous treatments.
Synonyms: (5aR,6S,8S,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo[3,2-b]quinolizine-8,13-diolCategories: Antiarrhythmics, Class I, Heterocyclic Compounds, 2-RingInvasive Meningococcal Infection caused by Neisseria meningitidis serogroup Y
go.drugbank.com/conditions/DBCOND0093729Drugs: Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine · Meningococcal polysaccharide vaccine group Y · Neisseria meningitidis group A capsular polysaccharide tetanus toxoid conjugate antigen · Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigenSynonyms: Invasive Infection caused by Neisseria meningitidis serogroup Y, Invasive Meningococcal Infection caused by Neisseria meningitidis serogroup YEprosartan
go.drugbank.com/drugs/DB00876ApprovedInvestigationalIt performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. … By inhibiting norepinephrine production, blood pressure is further reduced.
Synonyms: (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid, (E)-2-butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acidMixtures: Teveten Plus 600 mg/12,5 mg Filmtabletten, TEVETEN PLUS 600 MG/12.5 MG FİLM KAPLI TABLET, 28 ADETEnflurane
go.drugbank.com/drugs/DB00228ApprovedVet approvedWithdrawnEnflurane is a halogenated inhalational anesthetic initially approved by the FDA in 1972. Since this date, it has been withdrawn from the US market.
Synonyms: 2-chloro-1,1,2-trifluoroethyl difluoromethyl etherCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalIt is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: ROPINIROLO EG, ROPINIROLO EG STADAAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceuticalAlfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. … Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D].
Synonyms: 1-hydroxycholecalciferolCategories: Vitamin D and AnaloguesDolichovespula maculata venom protein
go.drugbank.com/drugs/DB10958ApprovedDolichovespula maculata venom protein is an extract of Dolichovespula maculata venom. Dolichovespula maculata venom protein is used in allergenic testing.
Mixtures: Mixed Vespid Venom Protein Multidose 13.0 Ml (3900 Mcg), Hymenoptera Venom Product-mixed Vespid Venom Protein (1650 Mcg)Products: Hymenoptera Venom Product-white-faced Hornet Venom Protein (550 Mcg), Venomil Inj 10mcg/ml White Faced HornetClevidipine
go.drugbank.com/drugs/DB04920ApprovedInvestigationalClevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: Cleviprex 0,5 mg/ml Emulsion zur Injektion