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Brexpiprazole
go.drugbank.com/drugs/DB09128ApprovedInvestigationalBrexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM). … It also displays stronger antagonism at the 5-HT1A and 5-HT2A receptors.[A182186, A38385, A259661] Brexpiprazole was first approved by the FDA on July 10, 2015.
Synonyms: Lu-AF41156Categories: Dopamine D2 Receptor Agonists, Cytochrome P-450 SubstratesBenralizumab
go.drugbank.com/drugs/DB12023ApprovedInvestigational[A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R, thus blocking signal transduction. … It is an afucosylated IgG which gives it high affinity for the FcγRIIIα receptor in natural killer cells, macrophages and neutrophils.
Products: FASENRA 30 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, Fasenra 30 mg solution for injection in pre-filled syringeTravoprost
go.drugbank.com/drugs/DB00287ApprovedInvestigationalTravoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. … [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher efficacy in reducing intraocular pressure and a reduced
Synonyms: -TRIFLUORO-M-TOLYL)OXY)-1-BUTENYL)CYCLOPENTYL)-5-HEPTENOATE, isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(α,α,α-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoateMixtures: TRAVAPRESS DUO 40 MCG+5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, TRAVO/TIMOL AL 40UG/ML+5MGFenoterol
go.drugbank.com/drugs/DB01288ApprovedWithdrawnFenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.
Mixtures: NOTECORT 20 MCG / 50 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 1 ADET, NOTECORT 20 MCG / 50 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 3 ADETProducts: Berotec 100 µg - Dosieraerosol, Berotec 1mg/mlRavulizumab
go.drugbank.com/drugs/DB11580ApprovedInvestigationalRavulizumab is a potent and selective complement 5 (C5) inhibitor. It is a humanized monoclonal IgG2/4 kappa antibody produced in Chinese hamster ovary (CHO) cells.
Products: Ultomiris 300 mg/3 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (1 adet), ULTOMIRIS ® RAVULIZUMAB 100MG/ML.Sodium glycerophosphate
go.drugbank.com/drugs/DB09561ApprovedSodium glycerophosphate is one of several glycerophosphate salts. It is used clinically to treat or prevent low phosphate levels [FDA Label]. Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body . The extent of ...
Mixtures: KABIVEN 1540 ML, AMINOMIX 1 NOVUM 1500 MLProducts: GLYCOPHOS CONCENTRATE FOR SOLUTION FOR INFUSION 216 mg/ml, Glycophos 6 g/20 ml Konzentrat zur Herstellung einer InfusionslösungRoflumilast
go.drugbank.com/drugs/DB01656ApprovedInvestigational[L46541] On December 15, 2023, the FDA approved a new topical foam formulation of roflumilast for the treatment of seborrheic dermatitis in patients aged 9 years and older.[L49281] … Roflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ROFLUNG 0,5 MG SAŞE ,30 SAŞE, ROFLUNG 0,5 MG SAŞE ,90 SAŞESufentanil
go.drugbank.com/drugs/DB00708ApprovedInvestigationalSufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. … Also known as _Dsuvia_, the sublingual form is used for the management of acute pain in adults that is severe to warrant the use of an opioid analgesic in certified medically supervised healthcare settings
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Sufentanil-hameln 10 Mikrogramm/ml Injektions-/Infusionslösung, Sufentanil Panpharma 50 Mikrogramm/ml InjektionslösungSomatostatin
go.drugbank.com/drugs/DB09099ApprovedInvestigationalWithdrawnThe actions of somatostatin are mediated via signalling pathways of G protein-coupled somatostatin receptors. … It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: SOMATOSTATIN EUMEDICA 250 MCG IV INFÜZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET, STILAMIN 3000 FOR INJECTION 3 mg/ampouleIpilimumab
go.drugbank.com/drugs/DB06186ApprovedInvestigationalIpilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4). … [L12126] Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.[A35065,A35080,L12126] Ipilimumab was developed by Bristol-Myers Squibb and Medarex.
Categories: Immunoglobulin GProducts: YERVOY 5 mg/ml concentrate for solution for infusion, YERVOY®5 MG /ML SOLUCION INYECTABLE PARA INFUSION INTRAVENOSA