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Tarlatamab
go.drugbank.com/drugs/DB17256ApprovedInvestigational[L50743] Tarlatamab-dlle was approved by the FDA in May 2024 for use in patients who have failed previous round of platinum-based chemotherapy,[L50743,L50748] becoming the first DLL3-targeting bispecific
Veligrotug
go.drugbank.com/drugs/DB18976Approved[L63929] The FDA approved veligrotug-vvze on June 26, 2026, for the treatment of thyroid eye disease regardless of disease activity or duration.[L63798,L63929]
Turoctocog alfa
go.drugbank.com/drugs/DB09109Approved[A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104]
Orlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalIt was approved by the FDA for use in combination with a reduced-calorie diet in 1999.
Hexaminolevulinate
go.drugbank.com/drugs/DB06261ApprovedInvestigationalFood and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for Intravesical Solution, Photocure ASA), as an optical imaging agent for use in combination with the
Viloxazine
go.drugbank.com/drugs/DB09185ApprovedInvestigationalWithdrawnIn April 2021, an extended-release formulation of viloxazine under the brand name QELBREE was approved by the FDA for the treatment of attention deficit hyperactivity disorder (ADHD).[A247985]
Methylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalThe intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia.
Bremelanotide
go.drugbank.com/drugs/DB11653Approved[A179689] Bremelanotide was granted FDA approval on 21 June 2019.[L9635]
Defactinib
go.drugbank.com/drugs/DB12282ApprovedInvestigational[L53208,A273943] Defactinib was approved by the US FDA in May 2025 in a co-package alongside [avutometinib] (called Avmapki Fakzynja) for the treatment of recurrent KRAS-mutated low-grade serous ovarian
Remimazolam
go.drugbank.com/drugs/DB12404ApprovedInvestigational[A214852,A214857] Remimazolam was the first "soft" benzodiazepine analog to be developed[A214862] and was approved for use by the FDA in July 2020 under the brand name Byfavo.[L14722]